Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes
The diblock copolymer polystyrene-b-polyisocyanoalanine(2-thiophene-3-yl-ethyl)amide (PS–PIAT) was prepared by reacting the isocyanide monomer (1) with a Ni(II) initiator complex prepared from polystyrene amine (PS40NH2), either obtained...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2011
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| Online Access: | https://hdl.handle.net/10356/91382 http://hdl.handle.net/10220/6789 |
| _version_ | 1811697283986620416 |
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| author | Hans-Peter M. de Hoog Dennis M. Vriezema Madhavan Nallani Suzanne Kuiper Jeroen J. L. M. Cornelissen Alan E. Rowan Roeland J. M. Nolte |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Hans-Peter M. de Hoog Dennis M. Vriezema Madhavan Nallani Suzanne Kuiper Jeroen J. L. M. Cornelissen Alan E. Rowan Roeland J. M. Nolte |
| author_sort | Hans-Peter M. de Hoog |
| collection | NTU |
| description | The diblock copolymer polystyrene-b-polyisocyanoalanine(2-thiophene-3-yl-ethyl)amide (PS–PIAT)
was prepared by reacting the isocyanide monomer (1) with a Ni(II) initiator complex prepared from
polystyrene amine (PS40NH2), either obtained by atom transfer radical polymerization (ATRP) or
anionic polymerization (AP). It was found that polymerization of optically pure 1 followed first-order
kinetics in monomer concentration and resulted in the formation of insoluble block copolymers,
whereas the rate of polymerization of optical mixtures of 1 was retarded and yielded block copolymers
that were better soluble. Furthermore, PS–PIAT polymersomes of which the PS-block was prepared by
AP were more stable than polymersomes of which the PS-block was prepared by ATRP, as was
indicated by combined turbidity and dynamic light scattering (DLS) measurements on the aggregate
solutions. |
| first_indexed | 2024-10-01T07:52:48Z |
| format | Journal Article |
| id | ntu-10356/91382 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:52:48Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | ntu-10356/913822023-07-14T15:53:00Z Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes Hans-Peter M. de Hoog Dennis M. Vriezema Madhavan Nallani Suzanne Kuiper Jeroen J. L. M. Cornelissen Alan E. Rowan Roeland J. M. Nolte School of Materials Science & Engineering DRNTU::Engineering::Materials::Biomaterials The diblock copolymer polystyrene-b-polyisocyanoalanine(2-thiophene-3-yl-ethyl)amide (PS–PIAT) was prepared by reacting the isocyanide monomer (1) with a Ni(II) initiator complex prepared from polystyrene amine (PS40NH2), either obtained by atom transfer radical polymerization (ATRP) or anionic polymerization (AP). It was found that polymerization of optically pure 1 followed first-order kinetics in monomer concentration and resulted in the formation of insoluble block copolymers, whereas the rate of polymerization of optical mixtures of 1 was retarded and yielded block copolymers that were better soluble. Furthermore, PS–PIAT polymersomes of which the PS-block was prepared by AP were more stable than polymersomes of which the PS-block was prepared by ATRP, as was indicated by combined turbidity and dynamic light scattering (DLS) measurements on the aggregate solutions. Published version 2011-05-11T03:58:00Z 2019-12-06T18:04:41Z 2011-05-11T03:58:00Z 2019-12-06T18:04:41Z 2008 2008 Journal Article Hans-Peter, M. H., Dennis, M. V., Madhavan, N., Suzanne, K., Jeroen, J. L. M. C., Alan E. R., & Roeland, J. M. N. (2008). Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes. Soft matter, 4, 1003–1010. 1744-683X https://hdl.handle.net/10356/91382 http://hdl.handle.net/10220/6789 10.1039/b716044e 155292 en Soft matter 8 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Materials::Biomaterials Hans-Peter M. de Hoog Dennis M. Vriezema Madhavan Nallani Suzanne Kuiper Jeroen J. L. M. Cornelissen Alan E. Rowan Roeland J. M. Nolte Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes |
| title | Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes |
| title_full | Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes |
| title_fullStr | Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes |
| title_full_unstemmed | Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes |
| title_short | Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes |
| title_sort | tuning the properties of ps piat block copolymers and their assembly into polymersomes |
| topic | DRNTU::Engineering::Materials::Biomaterials |
| url | https://hdl.handle.net/10356/91382 http://hdl.handle.net/10220/6789 |
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