Thermally mediated droplet formation in microchannels

Precise dispensing of microdroplets is an important process for droplet-based microfluidics. The droplet formation by shear force between two immiscible fluids depends on their flow rates, the viscosities, and the interfacial tension. In this letter, the authors report the use of integrated microhea...

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Main Authors: Nguyen, Nam-Trung, Ting, Teck-Hui, Yap, Yit Fatt, Wong, Teck Neng, Chai, John Chee Kiong, Ong, Wee-Liat, Zhou, Junlong, Tan, Say-Hwa, Yobas, Levent
Andre forfattere: School of Mechanical and Aerospace Engineering
Format: Journal Article
Sprog:English
Udgivet: 2012
Fag:
Online adgang:https://hdl.handle.net/10356/94428
http://hdl.handle.net/10220/7817
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author Nguyen, Nam-Trung
Ting, Teck-Hui
Yap, Yit Fatt
Wong, Teck Neng
Chai, John Chee Kiong
Ong, Wee-Liat
Zhou, Junlong
Tan, Say-Hwa
Yobas, Levent
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Nguyen, Nam-Trung
Ting, Teck-Hui
Yap, Yit Fatt
Wong, Teck Neng
Chai, John Chee Kiong
Ong, Wee-Liat
Zhou, Junlong
Tan, Say-Hwa
Yobas, Levent
author_sort Nguyen, Nam-Trung
collection NTU
description Precise dispensing of microdroplets is an important process for droplet-based microfluidics. The droplet formation by shear force between two immiscible fluids depends on their flow rates, the viscosities, and the interfacial tension. In this letter, the authors report the use of integrated microheater and temperature sensor for controlling the droplet formation process. The technique exploits the dependency on temperature of viscosities and interfacial tension. Using a relatively low heating temperature ranging from 25 to 70 °C, the droplet diameter can be adjusted to over two times of its original value. The relatively low temperature range makes sure that this concept is applicable for droplets containing biological samples
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spelling ntu-10356/944282023-03-04T17:18:26Z Thermally mediated droplet formation in microchannels Nguyen, Nam-Trung Ting, Teck-Hui Yap, Yit Fatt Wong, Teck Neng Chai, John Chee Kiong Ong, Wee-Liat Zhou, Junlong Tan, Say-Hwa Yobas, Levent School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering Precise dispensing of microdroplets is an important process for droplet-based microfluidics. The droplet formation by shear force between two immiscible fluids depends on their flow rates, the viscosities, and the interfacial tension. In this letter, the authors report the use of integrated microheater and temperature sensor for controlling the droplet formation process. The technique exploits the dependency on temperature of viscosities and interfacial tension. Using a relatively low heating temperature ranging from 25 to 70 °C, the droplet diameter can be adjusted to over two times of its original value. The relatively low temperature range makes sure that this concept is applicable for droplets containing biological samples Published version 2012-05-08T02:53:39Z 2019-12-06T18:55:51Z 2012-05-08T02:53:39Z 2019-12-06T18:55:51Z 2007 2007 Journal Article Nguyen, N. T., Ting, T. H., Yap, Y. F., Wong, T. N., Chai, J. C. K., Ong, W. L., et al. (2007). Thermally Mediated Droplet Formation in Microchannels. Applied Physics Letters, 91(8). 0003-6951 https://hdl.handle.net/10356/94428 http://hdl.handle.net/10220/7817 10.1063/1.2773948 131825 en Applied Physics Letters Applied physics letters © 2007 American Institute of Physics. This paper was published in Applied Physics Letters and is made available as an electronic reprint (preprint) with permission of American Institute of Physics. The paper can be found at DOI: [http://link.aip.org/link/doi/10.1063/1.2773948]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 4 p. application/pdf
spellingShingle DRNTU::Engineering::Mechanical engineering
Nguyen, Nam-Trung
Ting, Teck-Hui
Yap, Yit Fatt
Wong, Teck Neng
Chai, John Chee Kiong
Ong, Wee-Liat
Zhou, Junlong
Tan, Say-Hwa
Yobas, Levent
Thermally mediated droplet formation in microchannels
title Thermally mediated droplet formation in microchannels
title_full Thermally mediated droplet formation in microchannels
title_fullStr Thermally mediated droplet formation in microchannels
title_full_unstemmed Thermally mediated droplet formation in microchannels
title_short Thermally mediated droplet formation in microchannels
title_sort thermally mediated droplet formation in microchannels
topic DRNTU::Engineering::Mechanical engineering
url https://hdl.handle.net/10356/94428
http://hdl.handle.net/10220/7817
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AT wongteckneng thermallymediateddropletformationinmicrochannels
AT chaijohncheekiong thermallymediateddropletformationinmicrochannels
AT ongweeliat thermallymediateddropletformationinmicrochannels
AT zhoujunlong thermallymediateddropletformationinmicrochannels
AT tansayhwa thermallymediateddropletformationinmicrochannels
AT yobaslevent thermallymediateddropletformationinmicrochannels