Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs

In this contribution, we demonstrate a simple carbon nanotube device to electrically detect the presence of bacteria (Escherichai coli) with high sensitivity (<100 cfu/mL) and the glucose triggered metabolic activities of bacteria in real-time. As proof-of-concept demonstration, we...

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Main Authors: Huang, Yinxi, Sudibya, Herry Gunadi, Chen, Peng
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/94488
http://hdl.handle.net/10220/7548
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author Huang, Yinxi
Sudibya, Herry Gunadi
Chen, Peng
author2 School of Chemical and Biomedical Engineering
author_facet School of Chemical and Biomedical Engineering
Huang, Yinxi
Sudibya, Herry Gunadi
Chen, Peng
author_sort Huang, Yinxi
collection NTU
description In this contribution, we demonstrate a simple carbon nanotube device to electrically detect the presence of bacteria (Escherichai coli) with high sensitivity (<100 cfu/mL) and the glucose triggered metabolic activities of bacteria in real-time. As proof-of-concept demonstration, we also show that this nanoelectronic approach can be employed for high-throughput screening of anti-bacterial drugs.
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spelling ntu-10356/944882023-12-29T06:49:02Z Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs Huang, Yinxi Sudibya, Herry Gunadi Chen, Peng School of Chemical and Biomedical Engineering DRNTU::Engineering::Bioengineering In this contribution, we demonstrate a simple carbon nanotube device to electrically detect the presence of bacteria (Escherichai coli) with high sensitivity (<100 cfu/mL) and the glucose triggered metabolic activities of bacteria in real-time. As proof-of-concept demonstration, we also show that this nanoelectronic approach can be employed for high-throughput screening of anti-bacterial drugs. Accepted version 2012-02-28T09:15:52Z 2019-12-06T18:56:58Z 2012-02-28T09:15:52Z 2019-12-06T18:56:58Z 2011 2011 Journal Article Huang, Y., Sudibya, H. G., & Chen, P. (2011). Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs. Biosensors and Bioelectronics, 26, 4257–4261. https://hdl.handle.net/10356/94488 http://hdl.handle.net/10220/7548 10.1016/j.bios.2011.04.038 163171 en Biosensors and bioelectronics © 2011 Elsevier. This is the author created version of a work that has been peer reviewed and accepted for publication by Biosensors and Bioelectronics, Elsevier. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI: http://dx.doi.org/10.1016/j.bios.2011.04.038]. application/pdf
spellingShingle DRNTU::Engineering::Bioengineering
Huang, Yinxi
Sudibya, Herry Gunadi
Chen, Peng
Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs
title Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs
title_full Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs
title_fullStr Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs
title_full_unstemmed Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs
title_short Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs
title_sort detecting metabolic activities of bacteria using a simple carbon nanotube device for high throughput screening of anti bacterial drugs
topic DRNTU::Engineering::Bioengineering
url https://hdl.handle.net/10356/94488
http://hdl.handle.net/10220/7548
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