Passive micromixer for luminol-peroxide chemiluminescence detection

This paper reports a microchip with an integrated passive micromixer based on chaotic advection. The micromixer with staggered herringbone structures was used for luminol-peroxide chemiluminescence detection. The micromixer was examined to assess its suitability for chemiluminescence reaction. The r...

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Main Authors: Lok, Khoi Seng, Kwok, Yien Chian, Nguyen, Nam-Trung
Other Authors: School of Mechanical and Aerospace Engineering
Format: Journal Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/94592
http://hdl.handle.net/10220/7770
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author Lok, Khoi Seng
Kwok, Yien Chian
Nguyen, Nam-Trung
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Lok, Khoi Seng
Kwok, Yien Chian
Nguyen, Nam-Trung
author_sort Lok, Khoi Seng
collection NTU
description This paper reports a microchip with an integrated passive micromixer based on chaotic advection. The micromixer with staggered herringbone structures was used for luminol-peroxide chemiluminescence detection. The micromixer was examined to assess its suitability for chemiluminescence reaction. The relationship between the flow rate and the location of maximum chemiluminescence intensity was investigated. The light intensity was detected using an optical fiber attached along the mixing channel and a photon detector. A linear correlation between chemiluminescence intensity and the concentration of cobalt(II) ions or hydrogen peroxide was observed. This microchip has a potential application in environmental monitoring for industries involved in heavy metals and in medical diagnostics.
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spelling ntu-10356/945922023-03-04T17:14:07Z Passive micromixer for luminol-peroxide chemiluminescence detection Lok, Khoi Seng Kwok, Yien Chian Nguyen, Nam-Trung School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering This paper reports a microchip with an integrated passive micromixer based on chaotic advection. The micromixer with staggered herringbone structures was used for luminol-peroxide chemiluminescence detection. The micromixer was examined to assess its suitability for chemiluminescence reaction. The relationship between the flow rate and the location of maximum chemiluminescence intensity was investigated. The light intensity was detected using an optical fiber attached along the mixing channel and a photon detector. A linear correlation between chemiluminescence intensity and the concentration of cobalt(II) ions or hydrogen peroxide was observed. This microchip has a potential application in environmental monitoring for industries involved in heavy metals and in medical diagnostics. Accepted version 2012-04-12T08:26:45Z 2019-12-06T18:58:50Z 2012-04-12T08:26:45Z 2019-12-06T18:58:50Z 2011 2011 Journal Article Lok, K. S., Kwok, Y. C., & Nguyen, N. T. (2011). Passive Micromixer for Luminol-peroxide Chemiluminescence Detection. Analyst, 136, 2586-2591. https://hdl.handle.net/10356/94592 http://hdl.handle.net/10220/7770 10.1039/c1an15280g 159458 en Analyst © 2011 The Royal Society of Chemistry. This is the author created version of a work that has been peer reviewed and accepted for publication by Analyst, The Royal Society of Chemistry 2011. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI: http://dx.doi.org/10.1039/c1an15280g]. 17 p. application/pdf
spellingShingle DRNTU::Engineering::Mechanical engineering
Lok, Khoi Seng
Kwok, Yien Chian
Nguyen, Nam-Trung
Passive micromixer for luminol-peroxide chemiluminescence detection
title Passive micromixer for luminol-peroxide chemiluminescence detection
title_full Passive micromixer for luminol-peroxide chemiluminescence detection
title_fullStr Passive micromixer for luminol-peroxide chemiluminescence detection
title_full_unstemmed Passive micromixer for luminol-peroxide chemiluminescence detection
title_short Passive micromixer for luminol-peroxide chemiluminescence detection
title_sort passive micromixer for luminol peroxide chemiluminescence detection
topic DRNTU::Engineering::Mechanical engineering
url https://hdl.handle.net/10356/94592
http://hdl.handle.net/10220/7770
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