Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2
Giving the metal the boot: The title reaction provides facile access to functionalized chiral ketones from chiral α,α′-disubstituted aldehydes in the presence of molecular oxygen (see scheme). The CC bond-cleavage approach offers an alternative or better method relative to the typical bond-forming s...
| Main Authors: | , , |
|---|---|
| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2012
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/94646 http://hdl.handle.net/10220/8117 |
| _version_ | 1824456282548994048 |
|---|---|
| author | Tiwari, Bhoopendra Zhang, Junming Chi, Robin Yonggui |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Tiwari, Bhoopendra Zhang, Junming Chi, Robin Yonggui |
| author_sort | Tiwari, Bhoopendra |
| collection | NTU |
| description | Giving the metal the boot: The title reaction provides facile access to functionalized chiral ketones from chiral α,α′-disubstituted aldehydes in the presence of molecular oxygen (see scheme). The CC bond-cleavage approach offers an alternative or better method relative to the typical bond-forming strategies used in synthesizing chiral ketones. |
| first_indexed | 2025-02-19T03:51:38Z |
| format | Journal Article |
| id | ntu-10356/94646 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-02-19T03:51:38Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | ntu-10356/946462020-03-07T12:31:30Z Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2 Tiwari, Bhoopendra Zhang, Junming Chi, Robin Yonggui School of Physical and Mathematical Sciences DRNTU::Engineering::Chemical engineering::Biochemical engineering Giving the metal the boot: The title reaction provides facile access to functionalized chiral ketones from chiral α,α′-disubstituted aldehydes in the presence of molecular oxygen (see scheme). The CC bond-cleavage approach offers an alternative or better method relative to the typical bond-forming strategies used in synthesizing chiral ketones. 2012-05-22T09:02:46Z 2019-12-06T18:59:36Z 2012-05-22T09:02:46Z 2019-12-06T18:59:36Z 2012 2012 Journal Article Tiwari, B., Zhang, J. & Chi, R. Y. (2012). Facile Access to Chiral Ketones through Metal-Free Oxidative CC Bond Cleavage of Aldehydes by O2. Angewandte Chemie International Edition, 51(8), 1911-1914. https://hdl.handle.net/10356/94646 http://hdl.handle.net/10220/8117 10.1002/anie.201107473 165026 en Angewandte chemie international edition © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| spellingShingle | DRNTU::Engineering::Chemical engineering::Biochemical engineering Tiwari, Bhoopendra Zhang, Junming Chi, Robin Yonggui Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2 |
| title | Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2 |
| title_full | Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2 |
| title_fullStr | Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2 |
| title_full_unstemmed | Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2 |
| title_short | Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2 |
| title_sort | facile access to chiral ketones through metal free oxidative c c bond cleavage of aldehydes by o2 |
| topic | DRNTU::Engineering::Chemical engineering::Biochemical engineering |
| url | https://hdl.handle.net/10356/94646 http://hdl.handle.net/10220/8117 |
| work_keys_str_mv | AT tiwaribhoopendra facileaccesstochiralketonesthroughmetalfreeoxidativeccbondcleavageofaldehydesbyo2 AT zhangjunming facileaccesstochiralketonesthroughmetalfreeoxidativeccbondcleavageofaldehydesbyo2 AT chirobinyonggui facileaccesstochiralketonesthroughmetalfreeoxidativeccbondcleavageofaldehydesbyo2 |