Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-) : H2O2 ratio and confers anoikis resistance to tumors

Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-) : H2O2 ratio and confers anoikis resistance to tumors

Cancer is a leading cause of death worldwide. Tumor cells exploit various signaling pathways to promote their growth and metastasis. To our knowledge, the role of angiopoietin-like 4 protein (ANGPTL4) in cancer remains undefined. Here, we found that elevated ANGPTL4 expression is widespread in tumor...

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Bibliographic Details
Main Authors: Zhu, Pengcheng, Tan, Ming Jie, Huang, Royston-Luke, Tan, Chek Kun, Chong, Han Chung, Pal, Mintu, Lam, Ivan Chee Ren, Boukamp, Petra, Pan, Jiun Yit, Tan, Suat Hoon, Kersten, Sander, Li, Hoi-Yeung, Ding, Jeak Ling, Tan, Nguan Soon
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2012
Subjects:
DRNTU::Science::Biological sciences::Cytology
Online Access:https://hdl.handle.net/10356/94754
http://hdl.handle.net/10220/8177

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