Synthesis and application of novel β-CD derivatives as chiral stationary phases for supercritical fluid chromatography

Enantioseparation finds its greatest significance in pharmaceutical industry. Enantiomers of chiral drugs tend to show markedly different pharmacological activities. Currently, many commercial drugs are obtained as a mixture of two enantiomers through synthesis methods. In order to meet the demand o...

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Bibliographic Details
Main Author: Liu, Maolong
Other Authors: Ng Siu Choon
Format: Student Research Poster
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/95078
http://hdl.handle.net/10220/9008
Description
Summary:Enantioseparation finds its greatest significance in pharmaceutical industry. Enantiomers of chiral drugs tend to show markedly different pharmacological activities. Currently, many commercial drugs are obtained as a mixture of two enantiomers through synthesis methods. In order to meet the demand of enantiometric pure drugs, chromatographic methods have been used extensively in analysis, separation and purification of chiral compounds. [4th Award]