AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes

The recent development of microfluidic “lab on a chip” devices requires the need to continuously separate submicron particles. Here, we present a PDMS microfluidic device with sidewall conducting PDMS (AgPDMS) composite electrodes capable of separating submicron particles in hydrodynamic flow. In pa...

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Main Authors: Lewpiriyawong, Nuttawut, Yang, Chun
Other Authors: School of Mechanical and Aerospace Engineering
Format: Journal Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/95132
http://hdl.handle.net/10220/9174
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author Lewpiriyawong, Nuttawut
Yang, Chun
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Lewpiriyawong, Nuttawut
Yang, Chun
author_sort Lewpiriyawong, Nuttawut
collection NTU
description The recent development of microfluidic “lab on a chip” devices requires the need to continuously separate submicron particles. Here, we present a PDMS microfluidic device with sidewall conducting PDMS (AgPDMS) composite electrodes capable of separating submicron particles in hydrodynamic flow. In particular, the device can service dual functions. First, the AgPDMS composite electrodes embedded in a sidewall of the device channel allow for performing AC-dielectrophoretic (DEP) characterization through direct microscopic observation of particle behavior. Characterization experiments are carried out for numerous parameters including particle size, medium conductivity, and AC field frequency to reveal important dielectrophoresis DEP information in terms of the crossover frequency and positive/negative DEP behavior under specific frequencies. Second, the device offers an advantage that sidewall AgPDMS composite electrodes can produce strong DEP effects throughout the entire channel height, and thus the robustness of the on-chip particle separation is demonstrated for continuous separation in a flowing mixture of 0.5 and 5 μm particles with 100% separation efficiency.
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spelling ntu-10356/951322023-03-04T17:18:23Z AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes Lewpiriyawong, Nuttawut Yang, Chun School of Mechanical and Aerospace Engineering The recent development of microfluidic “lab on a chip” devices requires the need to continuously separate submicron particles. Here, we present a PDMS microfluidic device with sidewall conducting PDMS (AgPDMS) composite electrodes capable of separating submicron particles in hydrodynamic flow. In particular, the device can service dual functions. First, the AgPDMS composite electrodes embedded in a sidewall of the device channel allow for performing AC-dielectrophoretic (DEP) characterization through direct microscopic observation of particle behavior. Characterization experiments are carried out for numerous parameters including particle size, medium conductivity, and AC field frequency to reveal important dielectrophoresis DEP information in terms of the crossover frequency and positive/negative DEP behavior under specific frequencies. Second, the device offers an advantage that sidewall AgPDMS composite electrodes can produce strong DEP effects throughout the entire channel height, and thus the robustness of the on-chip particle separation is demonstrated for continuous separation in a flowing mixture of 0.5 and 5 μm particles with 100% separation efficiency. Published version 2013-02-20T01:48:51Z 2019-12-06T19:08:52Z 2013-02-20T01:48:51Z 2019-12-06T19:08:52Z 2012 2012 Journal Article Lewpiriyawong, N., & Yang, C. (2012). AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes. Biomicrofluidics, 6(1). 1932-1058 https://hdl.handle.net/10356/95132 http://hdl.handle.net/10220/9174 10.1063/1.3682049 22662074 en Biomicrofluidics © 2012 American Institute of Physics. This paper was published in Biomicrofluidics and is made available as an electronic reprint (preprint) with permission of American Institute of Physics. The paper can be found at the following official DOI: [http://dx.doi.org/10.1063/1.3682049]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. application/pdf
spellingShingle Lewpiriyawong, Nuttawut
Yang, Chun
AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes
title AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes
title_full AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes
title_fullStr AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes
title_full_unstemmed AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes
title_short AC-dielectrophoretic characterization and separation of submicron and micron particles using sidewall AgPDMS electrodes
title_sort ac dielectrophoretic characterization and separation of submicron and micron particles using sidewall agpdms electrodes
url https://hdl.handle.net/10356/95132
http://hdl.handle.net/10220/9174
work_keys_str_mv AT lewpiriyawongnuttawut acdielectrophoreticcharacterizationandseparationofsubmicronandmicronparticlesusingsidewallagpdmselectrodes
AT yangchun acdielectrophoreticcharacterizationandseparationofsubmicronandmicronparticlesusingsidewallagpdmselectrodes