Understanding the impact of angiopoietin-like protein 4 (ANGPTL4) on keratinocytes migration and proliferation using time lapse microscopy and live cell imaging
Skin wound healing involves both epithelia cell proliferation and migration, which are modulated by numerous secretory factors. Fasting-induced Adipose Factor (FIAF) was shown to be upregulated during wound healing, however its effects on migration and proliferation of keratinocytes remains unclear....
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| Format: | Student Research Poster |
| Language: | English |
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2013
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| Online Access: | https://hdl.handle.net/10356/95293 http://hdl.handle.net/10220/8992 |
| Summary: | Skin wound healing involves both epithelia cell proliferation and migration, which are modulated by numerous secretory factors. Fasting-induced Adipose Factor (FIAF) was shown to be upregulated during wound healing, however its effects on migration and proliferation of keratinocytes remains unclear. By using immortalized form of keratinocytes (HaCaT) and FIAF-knockdown keratinocytes (HaCaTKD) with and without proliferation inhibitor (Mitomycin C), we aim to determine the effect of FIAF on keratinocyte migration and proliferation during wound healing. [4th Award] |
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