Formal [4 + 1]- and [5 + 1]-annulation by an SN2–conjugate addition sequence : stereoselective synthesis of highly substituted carbocycles
K2CO3-mediated reactions of 6-bromo-2-hexenoates and 7-bromo-2-heptenoate with active methylene compounds deliver highly substituted cyclopentane and cyclohexane derivatives, respectively via a sequence of SN2–conjugate addition reactions (formal [4 + 1]- and [5 + 1]-annulation) in a diastereoselect...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/96126 http://hdl.handle.net/10220/10606 |
| _version_ | 1826127981811073024 |
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| author | Heng, Yi Li Chiba, Shunsuke Tong, Benny Meng Kiat Chen, Hui Chong, Sin Yee |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Heng, Yi Li Chiba, Shunsuke Tong, Benny Meng Kiat Chen, Hui Chong, Sin Yee |
| author_sort | Heng, Yi Li |
| collection | NTU |
| description | K2CO3-mediated reactions of 6-bromo-2-hexenoates and 7-bromo-2-heptenoate with active methylene compounds deliver highly substituted cyclopentane and cyclohexane derivatives, respectively via a sequence of SN2–conjugate addition reactions (formal [4 + 1]- and [5 + 1]-annulation) in a diastereoselective manner. |
| first_indexed | 2024-10-01T07:17:24Z |
| format | Journal Article |
| id | ntu-10356/96126 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:17:24Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/961262020-03-07T12:37:06Z Formal [4 + 1]- and [5 + 1]-annulation by an SN2–conjugate addition sequence : stereoselective synthesis of highly substituted carbocycles Heng, Yi Li Chiba, Shunsuke Tong, Benny Meng Kiat Chen, Hui Chong, Sin Yee School of Physical and Mathematical Sciences K2CO3-mediated reactions of 6-bromo-2-hexenoates and 7-bromo-2-heptenoate with active methylene compounds deliver highly substituted cyclopentane and cyclohexane derivatives, respectively via a sequence of SN2–conjugate addition reactions (formal [4 + 1]- and [5 + 1]-annulation) in a diastereoselective manner. 2013-06-25T03:56:28Z 2019-12-06T19:26:08Z 2013-06-25T03:56:28Z 2019-12-06T19:26:08Z 2012 2012 Journal Article Tong, B. M. K., Chen, H., Chong, S. Y., Heng, Y. L., & Chiba, S. (2012). Formal [4 + 1]- and [5 + 1]-Annulation by an SN2–Conjugate Addition Sequence: Stereoselective Synthesis of Highly Substituted Carbocycles. Organic Letters, 14(11), 2826-2829. 1523-7060 https://hdl.handle.net/10356/96126 http://hdl.handle.net/10220/10606 10.1021/ol301044e en Organic letters © 2012 American Chemical Society. |
| spellingShingle | Heng, Yi Li Chiba, Shunsuke Tong, Benny Meng Kiat Chen, Hui Chong, Sin Yee Formal [4 + 1]- and [5 + 1]-annulation by an SN2–conjugate addition sequence : stereoselective synthesis of highly substituted carbocycles |
| title | Formal [4 + 1]- and [5 + 1]-annulation by an SN2–conjugate addition sequence : stereoselective synthesis of highly substituted carbocycles |
| title_full | Formal [4 + 1]- and [5 + 1]-annulation by an SN2–conjugate addition sequence : stereoselective synthesis of highly substituted carbocycles |
| title_fullStr | Formal [4 + 1]- and [5 + 1]-annulation by an SN2–conjugate addition sequence : stereoselective synthesis of highly substituted carbocycles |
| title_full_unstemmed | Formal [4 + 1]- and [5 + 1]-annulation by an SN2–conjugate addition sequence : stereoselective synthesis of highly substituted carbocycles |
| title_short | Formal [4 + 1]- and [5 + 1]-annulation by an SN2–conjugate addition sequence : stereoselective synthesis of highly substituted carbocycles |
| title_sort | formal 4 1 and 5 1 annulation by an sn2 conjugate addition sequence stereoselective synthesis of highly substituted carbocycles |
| url | https://hdl.handle.net/10356/96126 http://hdl.handle.net/10220/10606 |
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