Recent development of cyclodextrin chiral stationary phases and their applications in chromatography
The current article reviews the development and applications of novel cyclodextrin chiral stationary phases (CD-CSPs) in liquid chromatography (LC), capillary electrochromatography (CEC), gas chromatography (GC) and supercritical fluid chromatography (SFC) over the period of January 2007 to March 20...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/96820 http://hdl.handle.net/10220/11618 |
| _version_ | 1811694160784130048 |
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| author | Xiao, Yin Ng, Siu-Choon Tan, Thatt Yang Timothy Wang, Yong |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Xiao, Yin Ng, Siu-Choon Tan, Thatt Yang Timothy Wang, Yong |
| author_sort | Xiao, Yin |
| collection | NTU |
| description | The current article reviews the development and applications of novel cyclodextrin chiral stationary phases (CD-CSPs) in liquid chromatography (LC), capillary electrochromatography (CEC), gas chromatography (GC) and supercritical fluid chromatography (SFC) over the period of January 2007 to March 2012. The synthetic routes of CD-CSPs, as well as the presence of selective functional groups in effecting inclusion complexation and molecular interactions have been found to exert profound influence in the enantioseparation process. In this article, various synthetic and functional groups immobilization strategies of novel CD-CSPs, and their applications in chiral resolution using different chromatography techniques are discussed. After introducing the topic in Section 1, Section 2 describes novel CD-CSPs in LC applications, where the CSPs are classified according to its coating approaches (physical and chemical manners) for ease of readership. Section 3 discusses recent development of CD-CSPs in open tubular CEC (OT-CEC), packed-bed CEC (P-CEC), pseudostationary phase CEC (PSP-CEC) and monolithic CEC. The last part illustrates novel CD-CSPs in gas chromatography (GC) and supercritical fluid chromatography (SFC). |
| first_indexed | 2024-10-01T07:03:10Z |
| format | Journal Article |
| id | ntu-10356/96820 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:03:10Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/968202020-03-07T11:35:29Z Recent development of cyclodextrin chiral stationary phases and their applications in chromatography Xiao, Yin Ng, Siu-Choon Tan, Thatt Yang Timothy Wang, Yong School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering The current article reviews the development and applications of novel cyclodextrin chiral stationary phases (CD-CSPs) in liquid chromatography (LC), capillary electrochromatography (CEC), gas chromatography (GC) and supercritical fluid chromatography (SFC) over the period of January 2007 to March 2012. The synthetic routes of CD-CSPs, as well as the presence of selective functional groups in effecting inclusion complexation and molecular interactions have been found to exert profound influence in the enantioseparation process. In this article, various synthetic and functional groups immobilization strategies of novel CD-CSPs, and their applications in chiral resolution using different chromatography techniques are discussed. After introducing the topic in Section 1, Section 2 describes novel CD-CSPs in LC applications, where the CSPs are classified according to its coating approaches (physical and chemical manners) for ease of readership. Section 3 discusses recent development of CD-CSPs in open tubular CEC (OT-CEC), packed-bed CEC (P-CEC), pseudostationary phase CEC (PSP-CEC) and monolithic CEC. The last part illustrates novel CD-CSPs in gas chromatography (GC) and supercritical fluid chromatography (SFC). 2013-07-16T08:41:24Z 2019-12-06T19:35:26Z 2013-07-16T08:41:24Z 2019-12-06T19:35:26Z 2012 2012 Journal Article Xiao, Y., Ng, S.-C., Tan, T. Y. T., & Wang, Y. (2012). Recent development of cyclodextrin chiral stationary phases and their applications in chromatography. Journal of chromatography A, 1269, 52-68. 0021-9673 https://hdl.handle.net/10356/96820 http://hdl.handle.net/10220/11618 10.1016/j.chroma.2012.08.049 en Journal of chromatography A © 2012 Elsevier B.V. |
| spellingShingle | DRNTU::Engineering::Chemical engineering Xiao, Yin Ng, Siu-Choon Tan, Thatt Yang Timothy Wang, Yong Recent development of cyclodextrin chiral stationary phases and their applications in chromatography |
| title | Recent development of cyclodextrin chiral stationary phases and their applications in chromatography |
| title_full | Recent development of cyclodextrin chiral stationary phases and their applications in chromatography |
| title_fullStr | Recent development of cyclodextrin chiral stationary phases and their applications in chromatography |
| title_full_unstemmed | Recent development of cyclodextrin chiral stationary phases and their applications in chromatography |
| title_short | Recent development of cyclodextrin chiral stationary phases and their applications in chromatography |
| title_sort | recent development of cyclodextrin chiral stationary phases and their applications in chromatography |
| topic | DRNTU::Engineering::Chemical engineering |
| url | https://hdl.handle.net/10356/96820 http://hdl.handle.net/10220/11618 |
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