Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs

Nanobiomaterials, a field at the interface of biomaterials and nanotechnologies, when applied to tissue engineering applications, are usually perceived to resemble the cell microenvironment components or as a material strategy to instruct cells and alter cell behaviors. Therefore, they provide a cle...

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Main Authors: An, Jia, Chua, Chee Kai, Yu, Ting, Li, Huaqiong, Tan, Lay Poh
Other Authors: School of Materials Science & Engineering
Format: Journal Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/97029
http://hdl.handle.net/10220/17312
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author An, Jia
Chua, Chee Kai
Yu, Ting
Li, Huaqiong
Tan, Lay Poh
author2 School of Materials Science & Engineering
author_facet School of Materials Science & Engineering
An, Jia
Chua, Chee Kai
Yu, Ting
Li, Huaqiong
Tan, Lay Poh
author_sort An, Jia
collection NTU
description Nanobiomaterials, a field at the interface of biomaterials and nanotechnologies, when applied to tissue engineering applications, are usually perceived to resemble the cell microenvironment components or as a material strategy to instruct cells and alter cell behaviors. Therefore, they provide a clear understanding of the relationship between nanotechnologies and resulting cellular responses. This review will cover recent advances in nanobiomaterial research for applications in tissue engineering. In particular, recent developments in nanofibrous scaffolds, nanobiomaterial composites, hydrogel systems, laser-fabricated nanostructures and cell-based bioprinting methods to produce scaffolds with nanofeatures for tissue engineering are discussed. As in native niches of cells, where nanofeatures are constantly interacting and influencing cellular behavior, new generations of scaffolds will need to have these features to enable more desirable engineered tissues. Moving forward, tissue engineering will also have to address the issues of complexity and organization in tissues and organs.
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spelling ntu-10356/970292020-06-01T10:01:31Z Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs An, Jia Chua, Chee Kai Yu, Ting Li, Huaqiong Tan, Lay Poh School of Materials Science & Engineering School of Mechanical and Aerospace Engineering DRNTU::Engineering::Materials::Biomaterials Nanobiomaterials, a field at the interface of biomaterials and nanotechnologies, when applied to tissue engineering applications, are usually perceived to resemble the cell microenvironment components or as a material strategy to instruct cells and alter cell behaviors. Therefore, they provide a clear understanding of the relationship between nanotechnologies and resulting cellular responses. This review will cover recent advances in nanobiomaterial research for applications in tissue engineering. In particular, recent developments in nanofibrous scaffolds, nanobiomaterial composites, hydrogel systems, laser-fabricated nanostructures and cell-based bioprinting methods to produce scaffolds with nanofeatures for tissue engineering are discussed. As in native niches of cells, where nanofeatures are constantly interacting and influencing cellular behavior, new generations of scaffolds will need to have these features to enable more desirable engineered tissues. Moving forward, tissue engineering will also have to address the issues of complexity and organization in tissues and organs. 2013-11-05T07:35:24Z 2019-12-06T19:38:03Z 2013-11-05T07:35:24Z 2019-12-06T19:38:03Z 2013 2013 Journal Article An, J., Chua, C. K., Yu, T., Li, H., & Tan, L. P. (2013). Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs. Nanomedicine, 8(4), 591-602. https://hdl.handle.net/10356/97029 http://hdl.handle.net/10220/17312 10.2217/nnm.13.46 en Nanomedicine
spellingShingle DRNTU::Engineering::Materials::Biomaterials
An, Jia
Chua, Chee Kai
Yu, Ting
Li, Huaqiong
Tan, Lay Poh
Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs
title Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs
title_full Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs
title_fullStr Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs
title_full_unstemmed Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs
title_short Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs
title_sort advanced nanobiomaterial strategies for the development of organized tissue engineering constructs
topic DRNTU::Engineering::Materials::Biomaterials
url https://hdl.handle.net/10356/97029
http://hdl.handle.net/10220/17312
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