Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds
A direct coupling of unprotected indoles and α-halo ketones via in situ generated oxyallyl cation intermediates is described. The reactions efficiently afford α-indole carbonyl compounds with good to quantitative yields.
Main Authors: | Tang, Qiang, Chen, Xingkuan, Tiwari, Bhoopendra, Chi, Robin Yonggui |
---|---|
Other Authors: | School of Physical and Mathematical Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2013
|
Online Access: | https://hdl.handle.net/10356/97259 http://hdl.handle.net/10220/10633 |
Similar Items
-
Facile access to chiral ketones through metal-free oxidative C-C bond cleavage of aldehydes by O2
by: Tiwari, Bhoopendra, et al.
Published: (2012) -
Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines
by: Jiang, Kun, et al.
Published: (2013) -
Mild and efficient C2-alkenylation of indoles with alkynes catalyzed by a cobalt complex
by: Ding, Zhenhua, et al.
Published: (2013) -
Catalytic hydroboration of carbonyl compounds and pyridine derivatives with the NHC-parent silyliumylidene cation
by: Lee, Jiawen
Published: (2020) -
Prediction of NHC-catalyzed chemoselective functionalizations of carbonyl compounds : a general mechanistic map
by: Li, Xue, et al.
Published: (2022)