Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts
The first N-Heterocyclic Carbene (NHC) mediated activation of stable carboxylate esters to generate enolate intermediates is disclosed. The catalytically generated arylacetic ester enolates undergo enantioselective reactions with α,β-unsaturated imines.
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/97284 http://hdl.handle.net/10220/10637 |
| _version_ | 1811685004404588544 |
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| author | Hao, Lin Du, Yu Lv, Hui Chen, Xingkuan Jiang, Huishen Shao, Yaling Chi, Robin Yonggui |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Hao, Lin Du, Yu Lv, Hui Chen, Xingkuan Jiang, Huishen Shao, Yaling Chi, Robin Yonggui |
| author_sort | Hao, Lin |
| collection | NTU |
| description | The first N-Heterocyclic Carbene (NHC) mediated activation of stable carboxylate esters to generate enolate intermediates is disclosed. The catalytically generated arylacetic ester enolates undergo enantioselective reactions with α,β-unsaturated imines. |
| first_indexed | 2024-10-01T04:37:38Z |
| format | Journal Article |
| id | ntu-10356/97284 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:37:38Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/972842020-03-07T12:34:43Z Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts Hao, Lin Du, Yu Lv, Hui Chen, Xingkuan Jiang, Huishen Shao, Yaling Chi, Robin Yonggui School of Physical and Mathematical Sciences The first N-Heterocyclic Carbene (NHC) mediated activation of stable carboxylate esters to generate enolate intermediates is disclosed. The catalytically generated arylacetic ester enolates undergo enantioselective reactions with α,β-unsaturated imines. 2013-06-25T06:40:51Z 2019-12-06T19:40:53Z 2013-06-25T06:40:51Z 2019-12-06T19:40:53Z 2012 2012 Journal Article Hao, L., Du, Y., Lv, H., Chen, X., Jiang, H., Shao, Y., et al. (2012). Enantioselective Activation of Stable Carboxylate Esters as Enolate Equivalents via N-Heterocyclic Carbene Catalysts. Organic Letters, 14(8), 2154-2157. 1523-7060 https://hdl.handle.net/10356/97284 http://hdl.handle.net/10220/10637 10.1021/ol300676w 164430 en Organic letters © 2012 American Chemical Society. |
| spellingShingle | Hao, Lin Du, Yu Lv, Hui Chen, Xingkuan Jiang, Huishen Shao, Yaling Chi, Robin Yonggui Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts |
| title | Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts |
| title_full | Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts |
| title_fullStr | Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts |
| title_full_unstemmed | Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts |
| title_short | Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts |
| title_sort | enantioselective activation of stable carboxylate esters as enolate equivalents via n heterocyclic carbene catalysts |
| url | https://hdl.handle.net/10356/97284 http://hdl.handle.net/10220/10637 |
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