Acceptorless and base-free dehydrogenation of alcohols and amines using ruthenium-hydride complexes
An efficient, operatively simple, acceptorless, and base-free dehydrogenation of secondary alcohols and nitrogen-containing heterocyclic compounds was achieved by using readily available ruthenium hydride complexes as precatalysts. The complex RuH2(CO)(PPh3)3 (1) and Shvo’s complex (2) showed excell...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/98297 http://hdl.handle.net/10220/12337 |
| _version_ | 1826122681125175296 |
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| author | Muthaiah, Senthilkumar Hong, Soon Hyeok |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Muthaiah, Senthilkumar Hong, Soon Hyeok |
| author_sort | Muthaiah, Senthilkumar |
| collection | NTU |
| description | An efficient, operatively simple, acceptorless, and base-free dehydrogenation of secondary alcohols and nitrogen-containing heterocyclic compounds was achieved by using readily available ruthenium hydride complexes as precatalysts. The complex RuH2(CO)(PPh3)3 (1) and Shvo’s complex (2) showed excellent activities for the dehydrogenation of secondary alcohols and nitrogen containing heterocycles. In addition to complexes 1 and 2, the complex RuH2(PPh3)4 (3) also showed moderate to excellent activity for the acceptorless dehydrogenation of nitrogen-containing heterocyclic compounds. Kinetic studies on the oxidation reaction of 1-phenylethanol using complex 1 were carried out in the presence and the absence of external triphenylphosphine (PPh3). External addition of PPh3 had a negative influence on the rate of the reaction, which suggested that dissociation of PPh3 occurred during the course of the reaction. Hydrogen was evolved from the oxidation reaction of 1-phenylethanol by using 1 mol% of 1 (88%) and 2 (92%), which demonstrated the possible usage of the catalytic systems in hydrogen generation. |
| first_indexed | 2024-10-01T05:52:29Z |
| format | Journal Article |
| id | ntu-10356/98297 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:52:29Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/982972020-03-07T12:34:46Z Acceptorless and base-free dehydrogenation of alcohols and amines using ruthenium-hydride complexes Muthaiah, Senthilkumar Hong, Soon Hyeok School of Physical and Mathematical Sciences An efficient, operatively simple, acceptorless, and base-free dehydrogenation of secondary alcohols and nitrogen-containing heterocyclic compounds was achieved by using readily available ruthenium hydride complexes as precatalysts. The complex RuH2(CO)(PPh3)3 (1) and Shvo’s complex (2) showed excellent activities for the dehydrogenation of secondary alcohols and nitrogen containing heterocycles. In addition to complexes 1 and 2, the complex RuH2(PPh3)4 (3) also showed moderate to excellent activity for the acceptorless dehydrogenation of nitrogen-containing heterocyclic compounds. Kinetic studies on the oxidation reaction of 1-phenylethanol using complex 1 were carried out in the presence and the absence of external triphenylphosphine (PPh3). External addition of PPh3 had a negative influence on the rate of the reaction, which suggested that dissociation of PPh3 occurred during the course of the reaction. Hydrogen was evolved from the oxidation reaction of 1-phenylethanol by using 1 mol% of 1 (88%) and 2 (92%), which demonstrated the possible usage of the catalytic systems in hydrogen generation. 2013-07-26T01:59:53Z 2019-12-06T19:53:18Z 2013-07-26T01:59:53Z 2019-12-06T19:53:18Z 2012 2012 Journal Article Muthaiah, S., & Hong, S. H. (2012). Acceptorless and Base-Free Dehydrogenation of Alcohols and Amines using Ruthenium-Hydride Complexes. Advanced Synthesis & Catalysis, 354(16), 3045-3053. 1615-4150 https://hdl.handle.net/10356/98297 http://hdl.handle.net/10220/12337 10.1002/adsc.201200532 en Advanced synthesis & catalysis © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| spellingShingle | Muthaiah, Senthilkumar Hong, Soon Hyeok Acceptorless and base-free dehydrogenation of alcohols and amines using ruthenium-hydride complexes |
| title | Acceptorless and base-free dehydrogenation of alcohols and amines using ruthenium-hydride complexes |
| title_full | Acceptorless and base-free dehydrogenation of alcohols and amines using ruthenium-hydride complexes |
| title_fullStr | Acceptorless and base-free dehydrogenation of alcohols and amines using ruthenium-hydride complexes |
| title_full_unstemmed | Acceptorless and base-free dehydrogenation of alcohols and amines using ruthenium-hydride complexes |
| title_short | Acceptorless and base-free dehydrogenation of alcohols and amines using ruthenium-hydride complexes |
| title_sort | acceptorless and base free dehydrogenation of alcohols and amines using ruthenium hydride complexes |
| url | https://hdl.handle.net/10356/98297 http://hdl.handle.net/10220/12337 |
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