Intermolecular Mizoroki-Heck reaction of aliphatic olefins with high selectivity for substitution at the internal position

New ligand for old reaction: The title reaction of aryltriflates with aliphatic olefins leads to substitution at the internal position with high selectivity. The ratio of the desired isomer (shown in the scheme) to the sum of all other isomers is generally above 10:1. The key to success is the use o...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Lu, Yunpeng, Li, Yongxin, Zhou, Jianrong Steve, Qin, Liena, Ren, Xinfeng
مؤلفون آخرون: School of Physical and Mathematical Sciences
التنسيق: Journal Article
اللغة:English
منشور في: 2013
الوصول للمادة أونلاين:https://hdl.handle.net/10356/98452
http://hdl.handle.net/10220/12466
الوصف
الملخص:New ligand for old reaction: The title reaction of aryltriflates with aliphatic olefins leads to substitution at the internal position with high selectivity. The ratio of the desired isomer (shown in the scheme) to the sum of all other isomers is generally above 10:1. The key to success is the use of a ferrocene bisphosphine ligand (R= 1-naphthyl). The reaction can be easily scaled up, and minor isomers can be separated by chromatography.