Catalytic asymmetric [4+2] annulation initiated by an Aza-Rauhut-Currier reaction : facile entry to highly functionalized tetrahydropyridines

Under control: The first example of chiral amino phosphine catalysts for the title reaction between vinyl ketones and N-sulfonyl-1-aza-1,3-dienes has been developed. Under ambient conditions, this protocol provides straightforward access to densely functionalized, enantioenriched tetrahydropyridines...

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Main Authors: Shi, Zugui, Yu, Peiyuan, Loh, Teck-Peng, Zhong, Guofu
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/98453
http://hdl.handle.net/10220/12444
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author Shi, Zugui
Yu, Peiyuan
Loh, Teck-Peng
Zhong, Guofu
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Shi, Zugui
Yu, Peiyuan
Loh, Teck-Peng
Zhong, Guofu
author_sort Shi, Zugui
collection NTU
description Under control: The first example of chiral amino phosphine catalysts for the title reaction between vinyl ketones and N-sulfonyl-1-aza-1,3-dienes has been developed. Under ambient conditions, this protocol provides straightforward access to densely functionalized, enantioenriched tetrahydropyridines with high levels of sterecontrol in good to excellent yields.
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spelling ntu-10356/984532020-03-07T12:34:47Z Catalytic asymmetric [4+2] annulation initiated by an Aza-Rauhut-Currier reaction : facile entry to highly functionalized tetrahydropyridines Shi, Zugui Yu, Peiyuan Loh, Teck-Peng Zhong, Guofu School of Physical and Mathematical Sciences Under control: The first example of chiral amino phosphine catalysts for the title reaction between vinyl ketones and N-sulfonyl-1-aza-1,3-dienes has been developed. Under ambient conditions, this protocol provides straightforward access to densely functionalized, enantioenriched tetrahydropyridines with high levels of sterecontrol in good to excellent yields. 2013-07-29T04:43:56Z 2019-12-06T19:55:23Z 2013-07-29T04:43:56Z 2019-12-06T19:55:23Z 2012 2012 Journal Article Shi, Z., Yu, P., Loh, T. P., & Zhong, G. (2012). Catalytic Asymmetric [4+2] Annulation Initiated by an Aza-Rauhut-Currier Reaction: Facile Entry to Highly Functionalized Tetrahydropyridines. Angewandte Chemie International Edition, 51(31), 7825-7829. 1433-7851 https://hdl.handle.net/10356/98453 http://hdl.handle.net/10220/12444 10.1002/anie.201203316 en Angewandte chemie international edition © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
spellingShingle Shi, Zugui
Yu, Peiyuan
Loh, Teck-Peng
Zhong, Guofu
Catalytic asymmetric [4+2] annulation initiated by an Aza-Rauhut-Currier reaction : facile entry to highly functionalized tetrahydropyridines
title Catalytic asymmetric [4+2] annulation initiated by an Aza-Rauhut-Currier reaction : facile entry to highly functionalized tetrahydropyridines
title_full Catalytic asymmetric [4+2] annulation initiated by an Aza-Rauhut-Currier reaction : facile entry to highly functionalized tetrahydropyridines
title_fullStr Catalytic asymmetric [4+2] annulation initiated by an Aza-Rauhut-Currier reaction : facile entry to highly functionalized tetrahydropyridines
title_full_unstemmed Catalytic asymmetric [4+2] annulation initiated by an Aza-Rauhut-Currier reaction : facile entry to highly functionalized tetrahydropyridines
title_short Catalytic asymmetric [4+2] annulation initiated by an Aza-Rauhut-Currier reaction : facile entry to highly functionalized tetrahydropyridines
title_sort catalytic asymmetric 4 2 annulation initiated by an aza rauhut currier reaction facile entry to highly functionalized tetrahydropyridines
url https://hdl.handle.net/10356/98453
http://hdl.handle.net/10220/12444
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