The rise of pathogens : predation as a factor D driving the evolution of human pathogens in the environment
Bacteria in the environment must survive predation from bacteriophage, heterotrophic protists, and predatory bacteria. This selective pressure has resulted in the evolution of a variety of defense mechanisms, which can also function as virulence factors. Here we discuss the potential dual function o...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2013
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| Online Access: | https://hdl.handle.net/10356/98588 http://hdl.handle.net/10220/17555 |
| _version_ | 1811685995177836544 |
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| author | Erken, Martina Lutz, Carla McDougald, Diane |
| author2 | School of Biological Sciences |
| author_facet | School of Biological Sciences Erken, Martina Lutz, Carla McDougald, Diane |
| author_sort | Erken, Martina |
| collection | NTU |
| description | Bacteria in the environment must survive predation from bacteriophage, heterotrophic protists, and predatory bacteria. This selective pressure has resulted in the evolution of a variety of defense mechanisms, which can also function as virulence factors. Here we discuss the potential dual function of some of the mechanisms, which protect against heterotrophic protists, and how predation pressure leads to the evolution of pathogenicity. This is in accordance with the coincidental evolution hypothesis, which suggests that virulence factors arose as a response to other selective pressures, for example, predation rather than for virulence per se. In this review we discuss some of those environmental factors that may be associated with the rise of pathogens in the marine environment. In particular, we will discuss the role of heterotrophic protists in the evolution of virulence factors in marine bacteria. Finally, we will discuss the implications for expansion of current pathogens and emergence of new pathogens. |
| first_indexed | 2024-10-01T04:53:22Z |
| format | Journal Article |
| id | ntu-10356/98588 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:53:22Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/985882022-02-16T16:28:26Z The rise of pathogens : predation as a factor D driving the evolution of human pathogens in the environment Erken, Martina Lutz, Carla McDougald, Diane School of Biological Sciences Nanyang Environment and Water Research Institute DRNTU::Science::Biological sciences Bacteria in the environment must survive predation from bacteriophage, heterotrophic protists, and predatory bacteria. This selective pressure has resulted in the evolution of a variety of defense mechanisms, which can also function as virulence factors. Here we discuss the potential dual function of some of the mechanisms, which protect against heterotrophic protists, and how predation pressure leads to the evolution of pathogenicity. This is in accordance with the coincidental evolution hypothesis, which suggests that virulence factors arose as a response to other selective pressures, for example, predation rather than for virulence per se. In this review we discuss some of those environmental factors that may be associated with the rise of pathogens in the marine environment. In particular, we will discuss the role of heterotrophic protists in the evolution of virulence factors in marine bacteria. Finally, we will discuss the implications for expansion of current pathogens and emergence of new pathogens. 2013-11-11T04:32:23Z 2019-12-06T19:57:09Z 2013-11-11T04:32:23Z 2019-12-06T19:57:09Z 2013 2013 Journal Article Erken, M., Lutz, C., & McDougald, D. (2013). The Rise of Pathogens: Predation as a Factor Driving the Evolution of Human Pathogens in the Environment. Microbial Ecology, 65(4), 860-868. https://hdl.handle.net/10356/98588 http://hdl.handle.net/10220/17555 10.1007/s00248-013-0189-0 23354181 en Microbial ecology |
| spellingShingle | DRNTU::Science::Biological sciences Erken, Martina Lutz, Carla McDougald, Diane The rise of pathogens : predation as a factor D driving the evolution of human pathogens in the environment |
| title | The rise of pathogens : predation as a factor D
driving the evolution of human pathogens in the environment |
| title_full | The rise of pathogens : predation as a factor D
driving the evolution of human pathogens in the environment |
| title_fullStr | The rise of pathogens : predation as a factor D
driving the evolution of human pathogens in the environment |
| title_full_unstemmed | The rise of pathogens : predation as a factor D
driving the evolution of human pathogens in the environment |
| title_short | The rise of pathogens : predation as a factor D
driving the evolution of human pathogens in the environment |
| title_sort | rise of pathogens predation as a factor d driving the evolution of human pathogens in the environment |
| topic | DRNTU::Science::Biological sciences |
| url | https://hdl.handle.net/10356/98588 http://hdl.handle.net/10220/17555 |
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