Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system
The E3 ubiquitin ligase Pellino 1 can be interconverted between inactive and active forms by a reversible phosphorylation mechanism. In vitro, phosphorylation and activation can be catalysed by either the IRAKs [IL (interleukin)-1-receptorassociated kinases] IRAK1 and IRAK4, or the IKK {IκB [in...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/98789 http://hdl.handle.net/10220/12739 |