Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO2) nanoparticles

Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO2) nanoparticles

The aim of this study is to uncover the size influence of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO2) nanoparticles on their potential cytotoxicity. PLGA and TiO2 nanoparticles of three different sizes were thoroughly characterized before in vitro cytotoxic tests which included...

Full description

Bibliographic Details
Main Authors:	Xiong, Sijing, George, Saji, Yu, Haiyang, Damoiseaux, Robert, France, Bryan, Ng, Kee Woei, Loo, Say Chye Joachim
Other Authors:	School of Materials Science & Engineering
Format:	Journal Article
Language:	English
Published:	2013
Online Access:	https://hdl.handle.net/10356/98977 http://hdl.handle.net/10220/12617

Similar Items

Size of TiO2 nanoparticles influences their phototoxicity : an in vitro investigation
by: Xiong, Sijing, et al.
Published: (2013)

Specific surface area of titanium dioxide (TiO2) particles influences cyto- and photo-toxicity
by: Xiong, Sijing, et al.
Published: (2013)

The effect of polyethylene glycol structure on paclitaxel drug release and mechanical properties of PLGA thin films
by: Steele, Terry W. J., et al.
Published: (2017)

Emerging In vitro models for safety screening of high-volume production nanomaterials under environmentally relevant exposure conditions
by: Kathawala, Mustafa Hussain, et al.
Published: (2014)

TiO2 nanoparticles alleviate toxicity by reducing free Zn2+ ion in human primary epidermal keratinocytes exposed to ZnO nanoparticles
by: Kathawala, Mustafa Hussain, et al.
Published: (2016)

Novel Fluorinated Poly (Lactic-Co-Glycolic acid) (PLGA) and Polyethylene Glycol (PEG) Nanoparticles for Monitoring and Imaging in Osteoarthritis
by: Luana Zerrillo, et al.
Published: (2021-02-01)

Biodegradation and Non-Enzymatic Hydrolysis of Poly(Lactic-<i>co</i>-Glycolic Acid) (PLGA12/88 and PLGA6/94)
by: Yue Wang, et al.
Published: (2021-12-01)

Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes
by: Loo, Joachim Say Chye, et al.
Published: (2014)

In Vitro Degradation of Electrospun Poly(Lactic-Co-Glycolic Acid) (PLGA) for Oral Mucosa Regeneration
by: Ana Chor, et al.
Published: (2020-08-01)

Nanoparticle-assay marker interaction: effects on nanotoxicity assessment
by: Zhao, Xinxin, et al.
Published: (2016)

TiO2-nanoparticles shield HPEKs against ZnO-induced genotoxicity
by: Kathawala, Mustafa Hussain, et al.
Published: (2016)

Topical Capsaicin in Poly(lactic-co-glycolic)acid (PLGA) Nanoparticles Decreases Acute Itch and Heat Pain
by: Nathalie M. Malewicz, et al.
Published: (2022-05-01)

Optimization of Methods for Determination of the Encapsulation Efficiency of Doxorubicin in the Nanoparticles Based on Poly(lactic-co-glycolic acid) (PLGA)
by: T. S. Kovshova, et al.
Published: (2020-05-01)

Modulating drug release from poly(lactic-co-glycolic acid) thin films through terminal end-groups and molecular weight
by: Boey, Freddy Yin Chiang, et al.
Published: (2014)

Novel gradient casting method provides high-throughput assessment of blended polyester poly(lactic-co-glycolic acid) thin films for parameter optimization
by: Venkatraman, Subbu S., et al.
Published: (2017)

Degradation and Characterisation of Electrospun Polycaprolactone (PCL) and Poly(lactic-co-glycolic acid) (PLGA) Scaffolds for Vascular Tissue Engineering
by: Morteza Bazgir, et al.
Published: (2021-08-01)

In Vitro and In Vivo Cell-Interactions with Electrospun Poly (Lactic-Co-Glycolic Acid) (PLGA): Morphological and Immune Response Analysis
by: Ana Chor, et al.
Published: (2022-10-01)

One-step fabrication of core–shell structured alginate–PLGA/PLLA microparticles as a novel drug delivery system for water soluble drugs
by: Lim, Ming Pin Alan, et al.
Published: (2016)

Cytotoxicity of hydroxyapatite nanoparticles is shape and cell dependent
by: Guo, Jun, et al.
Published: (2013)

Antibacterial 3D-Printed Silver Nanoparticle/Poly Lactic-Co-Glycolic Acid (PLGA) Scaffolds for Bone Tissue Engineering
by: Fajun Chen, et al.
Published: (2023-05-01)

PLGA‐PEG‐PLGA hydrogels induce cytotoxicity in conventional in vitro assays
by: Stewart, CL, et al.
Published: (2024)

اثر نانوذرات رزوراترول- Poly (lactic-co-glycolic acid) (PLGA) و نانوذرات کورکومین- PLGA به طور همزمان در تمایز سلولهای بنیادی مشتق از چربی به استئوبلاست
by: فاطمه عروجعلیان ., et al.
Published: (2022-02-01)

High-throughput screening of PLGA thin films utilizing hydrophobic fluorescent dyes for hydrophobic drug compounds
by: Steele, Terry W. J., et al.
Published: (2017)

Mechanical, thermal, and morphology properties of poly(lactic acid) plasticized with poly(ethylene glycol) and epoxidized palm oil hybrid plasticizer
by: Chieng, Buong Woei, et al.
Published: (2016)

An HPLC Method for Microanalysis and Pharmacokinetics of Marine Sulfated Polysaccharide PSS-Loaded Poly Lactic-co-Glycolic Acid (PLGA) Nanoparticles in Rat Plasma
by: Hua-Shi Guan, et al.
Published: (2013-04-01)

Chitosan Oleate Coated Poly Lactic-Glycolic Acid (PLGA) Nanoparticles versus Chitosan Oleate Self-Assembled Polymeric Micelles, Loaded with Resveratrol
by: Dalila Miele, et al.
Published: (2019-09-01)

MRI evaluation of resorbable poly lactic-co-glycolic acid (PLGA) screws used in pelvic osteotomies in children—a retrospective case series
by: Henrik Hedelin, et al.
Published: (2020-08-01)

Effect of electron beam radiation on the degradation of biopolymers
by: Loo, Joachim Say Chye
Published: (2008)

Preparation of Peptide and Recombinant Tissue Plasminogen Activator Conjugated Poly(Lactic-Co-Glycolic Acid) (PLGA) Magnetic Nanoparticles for Dual Targeted Thrombolytic Therapy
by: Huai-An Chen, et al.
Published: (2020-04-01)

Design of Poly(lactic-<i>co</i>-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis
by: Haitao Yang, et al.
Published: (2019-04-01)

Characteristic Evaluation of Recombinant MiSp/Poly(lactic-<i>co</i>-glycolic) Acid (PLGA) Nanofiber Scaffolds as Potential Scaffolds for Bone Tissue Engineering
by: Yuan Sun, et al.
Published: (2023-01-01)

Poly(lactic acid)/poly(ethylene glycol) polymer nanocomposites: effects of graphene nanoplatelets
by: Chieng, Buong Woei, et al.
Published: (2014)

Alleviation of Surgery-Induced Osteitis in Sinonasal Cavity by Dexamethasone-Loaded Poly(lactic-<i>co</i>-glycolic acid) (PLGA) Microparticles with Strong Calcium-Binding Affinity
by: Seung-No Hong, et al.
Published: (2022-02-01)

Melatonin loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles reduce inflammation, inhibit apoptosis and protect rat’s liver from the hazardous effects of CCL4
by: Alyaa Farid, et al.
Published: (2023-09-01)

Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
by: Yue Lu, et al.
Published: (2023-03-01)

Using screws from glycosyled lactic acid (PLGA) in the treatment of calcaneus fractures
by: S. A. Linnik, et al.
Published: (2020-11-01)

Injectable sustained‐release poly(lactic‐co‐glycolic acid) (PLGA) microspheres of exenatide prepared by supercritical fluid extraction of emulsion process based on a design of experiment approach
by: Heejun Park, et al.
Published: (2023-05-01)

Effects of annulus defects and implantation of poly(lactic-co-glycolic acid) (PLGA)/fibrin gel scaffolds on nerves ingrowth in a rabbit model of annular injury disc degeneration
by: Long Xin, et al.
Published: (2017-05-01)

Physicochemical, Antibacterial, and Cytotoxic Properties of Composite Materials Based on Biodegradable Poly (Lactic-Co-Glycolic Acid) Functionalized with Zno Nanoparticles
by: Burmistrov Dmitriy, et al.
Published: (2023-01-01)

Thermal characteristic of nanofluids containing titanium dioxide nanoparticles in ethylene glycol
by: Alias, H., et al.
Published: (2017)