Computational study of bindings of HK20 Fab and D5 Fab to HIV-1 gp41

Computational study of bindings of HK20 Fab and D5 Fab to HIV-1 gp41

Antibodies HK20 and D5 have been shown to target HIV-1 gp41, thereby inhibiting membrane fusion that facilitates viral entry. The binding picture is static, based on the X-ray crystal structures of the Fab regions and gp41 mimetic five-helix bundle. In this study, we carried out molecular dynamics s...

Bibliografski detalji
Glavni autori:	Hartono, Yossa Dwi, Lazim, Raudah, Yip, Yew Mun, Zhang, Dawei
Daljnji autori:	School of Physical and Mathematical Sciences
Format:	Journal Article
Jezik:	English
Izdano:	2013
Online pristup:	https://hdl.handle.net/10356/99036 http://hdl.handle.net/10220/12790

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