Interference of intrinsic curvature of DNA by DNA-intercalating agents

It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified throug...

Full description

Bibliographic Details
Main Authors: Tan, Hong Kee, Li, Dawei, Gray, Robert Kenneth, Yang, Zhaoqi, Ng, Magdeline Tao Tao, Zhang, Hao, Tan, Joel Ming Rui, Hiew, Shu Hui, Lee, Jasmine Yiqin, Li, Tianhu
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/99168
http://hdl.handle.net/10220/17249
_version_ 1826124992794853376
author Tan, Hong Kee
Li, Dawei
Gray, Robert Kenneth
Yang, Zhaoqi
Ng, Magdeline Tao Tao
Zhang, Hao
Tan, Joel Ming Rui
Hiew, Shu Hui
Lee, Jasmine Yiqin
Li, Tianhu
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Tan, Hong Kee
Li, Dawei
Gray, Robert Kenneth
Yang, Zhaoqi
Ng, Magdeline Tao Tao
Zhang, Hao
Tan, Joel Ming Rui
Hiew, Shu Hui
Lee, Jasmine Yiqin
Li, Tianhu
author_sort Tan, Hong Kee
collection NTU
description It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified through using an atomic force microscope.
first_indexed 2024-10-01T06:29:27Z
format Journal Article
id ntu-10356/99168
institution Nanyang Technological University
language English
last_indexed 2024-10-01T06:29:27Z
publishDate 2013
record_format dspace
spelling ntu-10356/991682020-03-07T12:31:21Z Interference of intrinsic curvature of DNA by DNA-intercalating agents Tan, Hong Kee Li, Dawei Gray, Robert Kenneth Yang, Zhaoqi Ng, Magdeline Tao Tao Zhang, Hao Tan, Joel Ming Rui Hiew, Shu Hui Lee, Jasmine Yiqin Li, Tianhu School of Physical and Mathematical Sciences It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified through using an atomic force microscope. 2013-11-05T04:43:36Z 2019-12-06T20:04:04Z 2013-11-05T04:43:36Z 2019-12-06T20:04:04Z 2012 2012 Journal Article Tan, H. K., Li, D., Gray, R. K., Yang, Z., Ng, M. T. T., Zhang, H., et al. (2012). Interference of intrinsic curvature of DNA by DNA-intercalating agents. Organic & Biomolecular Chemistry, 10(11), 2227-2230. https://hdl.handle.net/10356/99168 http://hdl.handle.net/10220/17249 10.1039/c2ob06811g en Organic & biomolecular chemistry
spellingShingle Tan, Hong Kee
Li, Dawei
Gray, Robert Kenneth
Yang, Zhaoqi
Ng, Magdeline Tao Tao
Zhang, Hao
Tan, Joel Ming Rui
Hiew, Shu Hui
Lee, Jasmine Yiqin
Li, Tianhu
Interference of intrinsic curvature of DNA by DNA-intercalating agents
title Interference of intrinsic curvature of DNA by DNA-intercalating agents
title_full Interference of intrinsic curvature of DNA by DNA-intercalating agents
title_fullStr Interference of intrinsic curvature of DNA by DNA-intercalating agents
title_full_unstemmed Interference of intrinsic curvature of DNA by DNA-intercalating agents
title_short Interference of intrinsic curvature of DNA by DNA-intercalating agents
title_sort interference of intrinsic curvature of dna by dna intercalating agents
url https://hdl.handle.net/10356/99168
http://hdl.handle.net/10220/17249
work_keys_str_mv AT tanhongkee interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT lidawei interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT grayrobertkenneth interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT yangzhaoqi interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT ngmagdelinetaotao interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT zhanghao interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT tanjoelmingrui interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT hiewshuhui interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT leejasmineyiqin interferenceofintrinsiccurvatureofdnabydnaintercalatingagents
AT litianhu interferenceofintrinsiccurvatureofdnabydnaintercalatingagents