Interference of intrinsic curvature of DNA by DNA-intercalating agents
It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified throug...
Main Authors: | , , , , , , , , , |
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Format: | Journal Article |
Language: | English |
Published: |
2013
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Online Access: | https://hdl.handle.net/10356/99168 http://hdl.handle.net/10220/17249 |
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author | Tan, Hong Kee Li, Dawei Gray, Robert Kenneth Yang, Zhaoqi Ng, Magdeline Tao Tao Zhang, Hao Tan, Joel Ming Rui Hiew, Shu Hui Lee, Jasmine Yiqin Li, Tianhu |
author2 | School of Physical and Mathematical Sciences |
author_facet | School of Physical and Mathematical Sciences Tan, Hong Kee Li, Dawei Gray, Robert Kenneth Yang, Zhaoqi Ng, Magdeline Tao Tao Zhang, Hao Tan, Joel Ming Rui Hiew, Shu Hui Lee, Jasmine Yiqin Li, Tianhu |
author_sort | Tan, Hong Kee |
collection | NTU |
description | It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified through using an atomic force microscope. |
first_indexed | 2024-10-01T06:29:27Z |
format | Journal Article |
id | ntu-10356/99168 |
institution | Nanyang Technological University |
language | English |
last_indexed | 2024-10-01T06:29:27Z |
publishDate | 2013 |
record_format | dspace |
spelling | ntu-10356/991682020-03-07T12:31:21Z Interference of intrinsic curvature of DNA by DNA-intercalating agents Tan, Hong Kee Li, Dawei Gray, Robert Kenneth Yang, Zhaoqi Ng, Magdeline Tao Tao Zhang, Hao Tan, Joel Ming Rui Hiew, Shu Hui Lee, Jasmine Yiqin Li, Tianhu School of Physical and Mathematical Sciences It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified through using an atomic force microscope. 2013-11-05T04:43:36Z 2019-12-06T20:04:04Z 2013-11-05T04:43:36Z 2019-12-06T20:04:04Z 2012 2012 Journal Article Tan, H. K., Li, D., Gray, R. K., Yang, Z., Ng, M. T. T., Zhang, H., et al. (2012). Interference of intrinsic curvature of DNA by DNA-intercalating agents. Organic & Biomolecular Chemistry, 10(11), 2227-2230. https://hdl.handle.net/10356/99168 http://hdl.handle.net/10220/17249 10.1039/c2ob06811g en Organic & biomolecular chemistry |
spellingShingle | Tan, Hong Kee Li, Dawei Gray, Robert Kenneth Yang, Zhaoqi Ng, Magdeline Tao Tao Zhang, Hao Tan, Joel Ming Rui Hiew, Shu Hui Lee, Jasmine Yiqin Li, Tianhu Interference of intrinsic curvature of DNA by DNA-intercalating agents |
title | Interference of intrinsic curvature of DNA by DNA-intercalating agents |
title_full | Interference of intrinsic curvature of DNA by DNA-intercalating agents |
title_fullStr | Interference of intrinsic curvature of DNA by DNA-intercalating agents |
title_full_unstemmed | Interference of intrinsic curvature of DNA by DNA-intercalating agents |
title_short | Interference of intrinsic curvature of DNA by DNA-intercalating agents |
title_sort | interference of intrinsic curvature of dna by dna intercalating agents |
url | https://hdl.handle.net/10356/99168 http://hdl.handle.net/10220/17249 |
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