A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields.
| Main Authors: | , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/99176 http://hdl.handle.net/10220/17155 |
| _version_ | 1826116631398449152 |
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| author | Chen, Ke Pullarkat, Sumod A. |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Chen, Ke Pullarkat, Sumod A. |
| author_sort | Chen, Ke |
| collection | NTU |
| description | A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields. |
| first_indexed | 2024-10-01T04:14:33Z |
| format | Journal Article |
| id | ntu-10356/99176 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:14:33Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/991762020-03-07T12:31:22Z A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines Chen, Ke Pullarkat, Sumod A. School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields. 2013-10-31T07:44:01Z 2019-12-06T20:04:08Z 2013-10-31T07:44:01Z 2019-12-06T20:04:08Z 2012 2012 Journal Article Chen, K., & Pullarkat, S. A. (2012). A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines. Organic & biomolecular chemistry, 10(32), 6600-6606. https://hdl.handle.net/10356/99176 http://hdl.handle.net/10220/17155 10.1039/c2ob25854d en Organic & biomolecular chemistry |
| spellingShingle | DRNTU::Science::Chemistry::Organic chemistry Chen, Ke Pullarkat, Sumod A. A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines |
| title | A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines |
| title_full | A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines |
| title_fullStr | A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines |
| title_full_unstemmed | A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines |
| title_short | A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines |
| title_sort | tandem heck aza michael addition protocol for the one pot synthesis of isoindolines from unprotected amines |
| topic | DRNTU::Science::Chemistry::Organic chemistry |
| url | https://hdl.handle.net/10356/99176 http://hdl.handle.net/10220/17155 |
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