The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (V-ATPase) and cytohesin-2

The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (V-ATPase) and cytohesin-2

Previously, we reported an acidification-dependent interaction of the endosomal vacuolar H+-ATPase (V-ATPase) with cytohesin-2, a GDP/GTP exchange factor (GEF), suggesting that it functions as a pH-sensing receptor. Here, we have studied the molecular mechanism of signaling between the V-ATPase, cyt...

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Bibliographic Details
Main Authors: Dip, Phat Vinh, Grüber, Gerhard, Marshansky, Vladimir, Hosokawa, H., Merkulova, M., Bakulina, A., Zhuang, Z., Khatri, A., Jian, X., Keating, S. M., Bueler, S. A., Rubinstein, J. L., Randazzo, P. A., Ausiello, D. A.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2013
Subjects:
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/99231
http://hdl.handle.net/10220/17563

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