The flavonoid myricetin reduces nocturnal melatonin levels in the blood through the inhibition of serotonin N-acetyltransferase
Melatonin is secreted during the hours of darkness and is thought to influence the circadian and seasonal timing of a variety of physiological processes. AANAT, which is expressed in the pineal gland, retina, and various other tissues, catalyzes the conversion of serotonin to N-acetylserotonin and i...
Main Authors: | Shin, Jae-Cheon, Jung, Hoe-Yune, Harikishore, Amaravadhi, Kwon, Oh-Deog, Yoon, Ho Sup, Kim, Kyong-Tai, Choi, Bo-Hwa |
---|---|
Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2013
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/99264 http://hdl.handle.net/10220/17391 |
Similar Items
-
Revisiting De Novo drug design : receptor based pharmacophore screening
by: Yoon, Ho Sup, et al.
Published: (2015) -
Solution structure of FK506-binding protein 12 from Aedes aegypti
by: Chakraborty, Goutam, et al.
Published: (2013) -
Combination of pharmacophore hypothesis and molecular docking to identify novel inhibitors of HCV NS5B polymerase
by: Harikishore, Amaravadhi, et al.
Published: (2015) -
Luteolin suppresses cancer cell proliferation by targeting vaccinia-related kinase 1
by: Kim, Ye Seul, et al.
Published: (2014) -
Relationship between nocturnal serotonin surge and melatonin onset in rodent pineal gland
by: Borjigin Jimo, et al.
Published: (2006-09-01)