Zinc oxide nanocomb biosensor for glucose detection
Single crystal zinc oxide nanocombs were synthesized in bulk quantity by vapor phase transport. A glucose biosensor was constructed using these nanocombs as supporting materials for glucose oxidase (GOx) loading. The zinc oxide nanocomb glucose biosensor showed a high sensitivity (15.33 μA/cm2 mM) f...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/99445 http://hdl.handle.net/10220/6884 |
| _version_ | 1826124191214075904 |
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| author | Wang, J. X. Sun, Xiaowei Wei, A. Lei, Y. Cai, X. P. Li, Chang Ming Dong, Zhili |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Wang, J. X. Sun, Xiaowei Wei, A. Lei, Y. Cai, X. P. Li, Chang Ming Dong, Zhili |
| author_sort | Wang, J. X. |
| collection | NTU |
| description | Single crystal zinc oxide nanocombs were synthesized in bulk quantity by vapor phase transport. A glucose biosensor was constructed using these nanocombs as supporting materials for glucose oxidase (GOx) loading. The zinc oxide nanocomb glucose biosensor showed a high sensitivity (15.33 μA/cm2 mM) for glucose detection and high affinity of GOx to glucose (the apparent Michaelis-Menten constant KMapp = 2.19 mM). The detection limit measured was 0.02 mM. These results demonstrate that zinc oxide nanostructures have potential applications in biosensors. |
| first_indexed | 2024-10-01T06:16:37Z |
| format | Journal Article |
| id | ntu-10356/99445 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:16:37Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | ntu-10356/994452023-07-14T15:54:33Z Zinc oxide nanocomb biosensor for glucose detection Wang, J. X. Sun, Xiaowei Wei, A. Lei, Y. Cai, X. P. Li, Chang Ming Dong, Zhili School of Materials Science & Engineering DRNTU::Engineering::Materials::Biomaterials Single crystal zinc oxide nanocombs were synthesized in bulk quantity by vapor phase transport. A glucose biosensor was constructed using these nanocombs as supporting materials for glucose oxidase (GOx) loading. The zinc oxide nanocomb glucose biosensor showed a high sensitivity (15.33 μA/cm2 mM) for glucose detection and high affinity of GOx to glucose (the apparent Michaelis-Menten constant KMapp = 2.19 mM). The detection limit measured was 0.02 mM. These results demonstrate that zinc oxide nanostructures have potential applications in biosensors. Published version 2011-07-12T01:35:18Z 2019-12-06T20:07:26Z 2011-07-12T01:35:18Z 2019-12-06T20:07:26Z 2006 2006 Journal Article Wang, J. X., Sun, X., Wei, A., Lei, Y., Cai, X. P., Li, C. M., et al. (2006). ZnO oxide nanocomb biosensor for glucose detection. Applied Physics Letters, 88(23). https://hdl.handle.net/10356/99445 http://hdl.handle.net/10220/6884 10.1063/1.2210078 en Applied physics letters © 2006 American Institute of Physics. This paper was published in Applied Physics Letters and is made available as an electronic reprint (preprint) with permission of American Institute of Physics. The paper can be found at: [DOI: http://dx.doi.org/10.1063/1.2210078]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 3 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Materials::Biomaterials Wang, J. X. Sun, Xiaowei Wei, A. Lei, Y. Cai, X. P. Li, Chang Ming Dong, Zhili Zinc oxide nanocomb biosensor for glucose detection |
| title | Zinc oxide nanocomb biosensor for glucose detection |
| title_full | Zinc oxide nanocomb biosensor for glucose detection |
| title_fullStr | Zinc oxide nanocomb biosensor for glucose detection |
| title_full_unstemmed | Zinc oxide nanocomb biosensor for glucose detection |
| title_short | Zinc oxide nanocomb biosensor for glucose detection |
| title_sort | zinc oxide nanocomb biosensor for glucose detection |
| topic | DRNTU::Engineering::Materials::Biomaterials |
| url | https://hdl.handle.net/10356/99445 http://hdl.handle.net/10220/6884 |
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