N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters
Synthesizing synthons: The highly enantioselective title reaction is described. It employs catalytic amounts of N-heterocyclic carbene precursors and transforms a broad range of nitroalkenes, such as nitrodienes, nitroenynes, and nitrostyrenes, through reaction with a broad range of enals, into δ-ni...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/99527 http://hdl.handle.net/10220/12504 |
| _version_ | 1811679576544247808 |
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| author | Maji, Biswajit Ji, Li Wang, Siming Vedachalam, Seenuvasan Ganguly, Rakesh Liu, Xue-Wei |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Maji, Biswajit Ji, Li Wang, Siming Vedachalam, Seenuvasan Ganguly, Rakesh Liu, Xue-Wei |
| author_sort | Maji, Biswajit |
| collection | NTU |
| description | Synthesizing synthons: The highly enantioselective title reaction is described. It employs catalytic amounts of N-heterocyclic carbene precursors and transforms a broad range of nitroalkenes, such as nitrodienes, nitroenynes, and nitrostyrenes, through reaction with a broad range of enals, into δ-nitroesters via homoenolate intermediates (see scheme). |
| first_indexed | 2024-10-01T03:11:21Z |
| format | Journal Article |
| id | ntu-10356/99527 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:11:21Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/995272020-03-07T12:34:47Z N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters Maji, Biswajit Ji, Li Wang, Siming Vedachalam, Seenuvasan Ganguly, Rakesh Liu, Xue-Wei School of Physical and Mathematical Sciences DRNTU::Science::Chemistry Synthesizing synthons: The highly enantioselective title reaction is described. It employs catalytic amounts of N-heterocyclic carbene precursors and transforms a broad range of nitroalkenes, such as nitrodienes, nitroenynes, and nitrostyrenes, through reaction with a broad range of enals, into δ-nitroesters via homoenolate intermediates (see scheme). 2013-07-30T03:40:47Z 2019-12-06T20:08:23Z 2013-07-30T03:40:47Z 2019-12-06T20:08:23Z 2012 2012 Journal Article Maji, B., Ji, L., Wang, S., Vedachalam, S., Ganguly, R., & Liu, X.-W. (2012). N-Heterocyclic Carbene Catalyzed Homoenolate-Addition Reaction of Enals and Nitroalkenes: Asymmetric Synthesis of 5-Carbon-Synthon δ-Nitroesters. Angewandte Chemie International Edition, 51(33), 8276-8280. 1433-7851 https://hdl.handle.net/10356/99527 http://hdl.handle.net/10220/12504 10.1002/anie.201203449 en Angewandte chemie international edition © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| spellingShingle | DRNTU::Science::Chemistry Maji, Biswajit Ji, Li Wang, Siming Vedachalam, Seenuvasan Ganguly, Rakesh Liu, Xue-Wei N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters |
| title | N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters |
| title_full | N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters |
| title_fullStr | N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters |
| title_full_unstemmed | N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters |
| title_short | N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters |
| title_sort | n heterocyclic carbene catalyzed homoenolate addition reaction of enals and nitroalkenes asymmetric synthesis of 5 carbon synthon δ nitroesters |
| topic | DRNTU::Science::Chemistry |
| url | https://hdl.handle.net/10356/99527 http://hdl.handle.net/10220/12504 |
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