In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles

Trading up: A bioimaging system that is based on caged D-luciferin/upconversion nanoparticle conjugate has been developed. The nanoparticles upconvert near-infrared light into UV light, which triggers the photorelease of D-luciferin (see scheme) and leads to enhanced fluorescence and bioluminescence...

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Main Authors: Wang, Chao, Teng, Xue, Cheng, Kai, Cheng, Zhen, Huang, Ling, Liu, Zhuang, Liu, Xiaogang, Xing, Bengang, Yang, Yanmei, Shao, Qing, Deng, Renren
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/99542
http://hdl.handle.net/10220/12461
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author Wang, Chao
Teng, Xue
Cheng, Kai
Cheng, Zhen
Huang, Ling
Liu, Zhuang
Liu, Xiaogang
Xing, Bengang
Yang, Yanmei
Shao, Qing
Deng, Renren
author2 School of Chemical and Biomedical Engineering
author_facet School of Chemical and Biomedical Engineering
Wang, Chao
Teng, Xue
Cheng, Kai
Cheng, Zhen
Huang, Ling
Liu, Zhuang
Liu, Xiaogang
Xing, Bengang
Yang, Yanmei
Shao, Qing
Deng, Renren
author_sort Wang, Chao
collection NTU
description Trading up: A bioimaging system that is based on caged D-luciferin/upconversion nanoparticle conjugate has been developed. The nanoparticles upconvert near-infrared light into UV light, which triggers the photorelease of D-luciferin (see scheme) and leads to enhanced fluorescence and bioluminescence signals in vitro and in vivo. The use of near-infrared light enables deep penetration into tissue in vivo with minimum cellular damage.
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spelling ntu-10356/995422020-03-07T12:34:48Z In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles Wang, Chao Teng, Xue Cheng, Kai Cheng, Zhen Huang, Ling Liu, Zhuang Liu, Xiaogang Xing, Bengang Yang, Yanmei Shao, Qing Deng, Renren School of Chemical and Biomedical Engineering School of Physical and Mathematical Sciences Trading up: A bioimaging system that is based on caged D-luciferin/upconversion nanoparticle conjugate has been developed. The nanoparticles upconvert near-infrared light into UV light, which triggers the photorelease of D-luciferin (see scheme) and leads to enhanced fluorescence and bioluminescence signals in vitro and in vivo. The use of near-infrared light enables deep penetration into tissue in vivo with minimum cellular damage. 2013-07-29T06:36:43Z 2019-12-06T20:08:32Z 2013-07-29T06:36:43Z 2019-12-06T20:08:32Z 2012 2012 Journal Article Yang, Y., Shao, Q., Deng, R., Wang, C., Teng, X., Cheng, K., et al. (2012). In Vitro and In Vivo Uncaging and Bioluminescence Imaging by Using Photocaged Upconversion Nanoparticles. Angewandte Chemie International Edition, 51(13), 3125-3129. 1433-7851 https://hdl.handle.net/10356/99542 http://hdl.handle.net/10220/12461 10.1002/anie.201107919 en Angewandte chemie international edition © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
spellingShingle Wang, Chao
Teng, Xue
Cheng, Kai
Cheng, Zhen
Huang, Ling
Liu, Zhuang
Liu, Xiaogang
Xing, Bengang
Yang, Yanmei
Shao, Qing
Deng, Renren
In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
title In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
title_full In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
title_fullStr In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
title_full_unstemmed In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
title_short In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
title_sort in vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
url https://hdl.handle.net/10356/99542
http://hdl.handle.net/10220/12461
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