Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography
Proteinase K is patterned on poly(L-lactic acid) (PLLA) film by agarose-assisted dip-pen nanolithography. Lateral biodegradation at the nanometer scale on PLLA film is faster than vertical biodegradation. The height and diameter of the patterned proteinase K dots can affect the depth of the biodegra...
Main Authors: | , , , , , , , , |
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Format: | Journal Article |
Language: | English |
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2012
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Online Access: | https://hdl.handle.net/10356/99642 http://hdl.handle.net/10220/8640 |
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author | Li, Hai He, Qiyuan Wang, Xiaohong Lu, Gang Liusman, Cipto Li, Bing Boey, Freddy Yin Chiang Venkatraman, Subbu S. Zhang, Hua |
author2 | School of Materials Science & Engineering |
author_facet | School of Materials Science & Engineering Li, Hai He, Qiyuan Wang, Xiaohong Lu, Gang Liusman, Cipto Li, Bing Boey, Freddy Yin Chiang Venkatraman, Subbu S. Zhang, Hua |
author_sort | Li, Hai |
collection | NTU |
description | Proteinase K is patterned on poly(L-lactic acid) (PLLA) film by agarose-assisted dip-pen nanolithography. Lateral biodegradation at the nanometer scale on PLLA film is faster than vertical biodegradation. The height and diameter of the patterned proteinase K dots can affect the depth of the biodegraded holes, while the concentration of the proteinase K solution (the ink used to coat the AFM tip) does not affect the biodegradation. |
first_indexed | 2024-10-01T04:13:35Z |
format | Journal Article |
id | ntu-10356/99642 |
institution | Nanyang Technological University |
language | English |
last_indexed | 2024-10-01T04:13:35Z |
publishDate | 2012 |
record_format | dspace |
spelling | ntu-10356/996422020-06-01T10:21:09Z Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography Li, Hai He, Qiyuan Wang, Xiaohong Lu, Gang Liusman, Cipto Li, Bing Boey, Freddy Yin Chiang Venkatraman, Subbu S. Zhang, Hua School of Materials Science & Engineering DRNTU::Engineering::Mechanical engineering Proteinase K is patterned on poly(L-lactic acid) (PLLA) film by agarose-assisted dip-pen nanolithography. Lateral biodegradation at the nanometer scale on PLLA film is faster than vertical biodegradation. The height and diameter of the patterned proteinase K dots can affect the depth of the biodegraded holes, while the concentration of the proteinase K solution (the ink used to coat the AFM tip) does not affect the biodegradation. 2012-09-26T07:11:05Z 2019-12-06T20:09:47Z 2012-09-26T07:11:05Z 2019-12-06T20:09:47Z 2011 2011 Journal Article Li, H., He, Q., Wang, X., Lu, G., Liusman, C., Li, B., et al. (2011). Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography. Small, 7(2), 226-229. 1613-6810 https://hdl.handle.net/10356/99642 http://hdl.handle.net/10220/8640 10.1002/smll.201001977 en Small © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
spellingShingle | DRNTU::Engineering::Mechanical engineering Li, Hai He, Qiyuan Wang, Xiaohong Lu, Gang Liusman, Cipto Li, Bing Boey, Freddy Yin Chiang Venkatraman, Subbu S. Zhang, Hua Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography |
title | Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography |
title_full | Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography |
title_fullStr | Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography |
title_full_unstemmed | Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography |
title_short | Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography |
title_sort | nanoscale controlled enzymatic degradation of poly l lactic acid films using dip pen nanolithography |
topic | DRNTU::Engineering::Mechanical engineering |
url | https://hdl.handle.net/10356/99642 http://hdl.handle.net/10220/8640 |
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