Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography

Proteinase K is patterned on poly(L-lactic acid) (PLLA) film by agarose-assisted dip-pen nanolithography. Lateral biodegradation at the nanometer scale on PLLA film is faster than vertical biodegradation. The height and diameter of the patterned proteinase K dots can affect the depth of the biodegra...

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Main Authors: Li, Hai, He, Qiyuan, Wang, Xiaohong, Lu, Gang, Liusman, Cipto, Li, Bing, Boey, Freddy Yin Chiang, Venkatraman, Subbu S., Zhang, Hua
Other Authors: School of Materials Science & Engineering
Format: Journal Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/99642
http://hdl.handle.net/10220/8640
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author Li, Hai
He, Qiyuan
Wang, Xiaohong
Lu, Gang
Liusman, Cipto
Li, Bing
Boey, Freddy Yin Chiang
Venkatraman, Subbu S.
Zhang, Hua
author2 School of Materials Science & Engineering
author_facet School of Materials Science & Engineering
Li, Hai
He, Qiyuan
Wang, Xiaohong
Lu, Gang
Liusman, Cipto
Li, Bing
Boey, Freddy Yin Chiang
Venkatraman, Subbu S.
Zhang, Hua
author_sort Li, Hai
collection NTU
description Proteinase K is patterned on poly(L-lactic acid) (PLLA) film by agarose-assisted dip-pen nanolithography. Lateral biodegradation at the nanometer scale on PLLA film is faster than vertical biodegradation. The height and diameter of the patterned proteinase K dots can affect the depth of the biodegraded holes, while the concentration of the proteinase K solution (the ink used to coat the AFM tip) does not affect the biodegradation.
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spelling ntu-10356/996422020-06-01T10:21:09Z Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography Li, Hai He, Qiyuan Wang, Xiaohong Lu, Gang Liusman, Cipto Li, Bing Boey, Freddy Yin Chiang Venkatraman, Subbu S. Zhang, Hua School of Materials Science & Engineering DRNTU::Engineering::Mechanical engineering Proteinase K is patterned on poly(L-lactic acid) (PLLA) film by agarose-assisted dip-pen nanolithography. Lateral biodegradation at the nanometer scale on PLLA film is faster than vertical biodegradation. The height and diameter of the patterned proteinase K dots can affect the depth of the biodegraded holes, while the concentration of the proteinase K solution (the ink used to coat the AFM tip) does not affect the biodegradation. 2012-09-26T07:11:05Z 2019-12-06T20:09:47Z 2012-09-26T07:11:05Z 2019-12-06T20:09:47Z 2011 2011 Journal Article Li, H., He, Q., Wang, X., Lu, G., Liusman, C., Li, B., et al. (2011). Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography. Small, 7(2), 226-229. 1613-6810 https://hdl.handle.net/10356/99642 http://hdl.handle.net/10220/8640 10.1002/smll.201001977 en Small © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
spellingShingle DRNTU::Engineering::Mechanical engineering
Li, Hai
He, Qiyuan
Wang, Xiaohong
Lu, Gang
Liusman, Cipto
Li, Bing
Boey, Freddy Yin Chiang
Venkatraman, Subbu S.
Zhang, Hua
Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography
title Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography
title_full Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography
title_fullStr Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography
title_full_unstemmed Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography
title_short Nanoscale-controlled enzymatic degradation of poly(L-lactic acid) films using dip-pen nanolithography
title_sort nanoscale controlled enzymatic degradation of poly l lactic acid films using dip pen nanolithography
topic DRNTU::Engineering::Mechanical engineering
url https://hdl.handle.net/10356/99642
http://hdl.handle.net/10220/8640
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