cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity
The first successful generation of cis-homoenolate equivalents from cis-enals under the catalysis of N-heterocyclic carbenes (NHCs) has been realized. The cis-homoenolate intermediates undergo effective reactions with α,β-unsaturated imines to afford chiral cyclic ketone products. Compared to the tr...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2013
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| Online Access: | https://hdl.handle.net/10356/99694 http://hdl.handle.net/10220/17475 |
| _version_ | 1826130090804641792 |
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| author | Chen, Xingkuan Fang, Xinqiang Chi, Robin Yonggui |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Chen, Xingkuan Fang, Xinqiang Chi, Robin Yonggui |
| author_sort | Chen, Xingkuan |
| collection | NTU |
| description | The first successful generation of cis-homoenolate equivalents from cis-enals under the catalysis of N-heterocyclic carbenes (NHCs) has been realized. The cis-homoenolate intermediates undergo effective reactions with α,β-unsaturated imines to afford chiral cyclic ketone products. Compared to the trans-enals, cis-enals show different stereoselectivities and new reactivity patterns. |
| first_indexed | 2024-10-01T07:50:51Z |
| format | Journal Article |
| id | ntu-10356/99694 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:50:51Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/996942020-03-07T12:34:48Z cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity Chen, Xingkuan Fang, Xinqiang Chi, Robin Yonggui School of Physical and Mathematical Sciences Physical and Mathematical Sciences The first successful generation of cis-homoenolate equivalents from cis-enals under the catalysis of N-heterocyclic carbenes (NHCs) has been realized. The cis-homoenolate intermediates undergo effective reactions with α,β-unsaturated imines to afford chiral cyclic ketone products. Compared to the trans-enals, cis-enals show different stereoselectivities and new reactivity patterns. 2013-11-08T06:12:07Z 2019-12-06T20:10:26Z 2013-11-08T06:12:07Z 2019-12-06T20:10:26Z 2013 2013 Journal Article Chen, X., Fang, X., & Chi, Y. R. (2013). cis-Enals in N-heterocyclic carbene-catalyzed reactions: distinct stereoselectivity and reactivity. Chemical Science, 4(6), 2613-2618. https://hdl.handle.net/10356/99694 http://hdl.handle.net/10220/17475 10.1039/c3sc50666e 173631 en Chemical science |
| spellingShingle | Physical and Mathematical Sciences Chen, Xingkuan Fang, Xinqiang Chi, Robin Yonggui cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title | cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_full | cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_fullStr | cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_full_unstemmed | cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_short | cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_sort | cis enals in n heterocyclic carbene catalyzed reactions distinct stereoselectivity and reactivity |
| topic | Physical and Mathematical Sciences |
| url | https://hdl.handle.net/10356/99694 http://hdl.handle.net/10220/17475 |
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