The application of graphene oxide in drug delivery

Introduction: As a shining star in material science, graphene oxide (GO) and its derivatives possess potential applications in a variety of areas. Among them, the application of GO to drug delivery has attracted ever-increasing interest in the past few years. Areas covered: In this article, the a...

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Main Authors: Pan, Yongzheng, Sahoo, Nanda Gopal, Li, Lin
Other Authors: School of Mechanical and Aerospace Engineering
Format: Journal Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/99938
http://hdl.handle.net/10220/13748
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author Pan, Yongzheng
Sahoo, Nanda Gopal
Li, Lin
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Pan, Yongzheng
Sahoo, Nanda Gopal
Li, Lin
author_sort Pan, Yongzheng
collection NTU
description Introduction: As a shining star in material science, graphene oxide (GO) and its derivatives possess potential applications in a variety of areas. Among them, the application of GO to drug delivery has attracted ever-increasing interest in the past few years. Areas covered: In this article, the authors summarize the latest progress of utilizing GO in the field of drug delivery. In particular, the functionalization of GO, cytotoxicity of GO and its derivatives, in vitro and in vivo drug delivery and the comparison with carbon nanotube-based delivery systems are discussed. Future perspectives and possible challenges in this emerging field are briefly described. Expert opinion: GO and its derivatives are highly attractive for the application to drug delivery due to their exceptional physiochemical properties and unique planar structure in spite of some existing challenges, such as the reproducibly smart functionalization of GO and the investigation of its long-term toxicology.
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spelling ntu-10356/999382020-03-07T13:22:19Z The application of graphene oxide in drug delivery Pan, Yongzheng Sahoo, Nanda Gopal Li, Lin School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering Introduction: As a shining star in material science, graphene oxide (GO) and its derivatives possess potential applications in a variety of areas. Among them, the application of GO to drug delivery has attracted ever-increasing interest in the past few years. Areas covered: In this article, the authors summarize the latest progress of utilizing GO in the field of drug delivery. In particular, the functionalization of GO, cytotoxicity of GO and its derivatives, in vitro and in vivo drug delivery and the comparison with carbon nanotube-based delivery systems are discussed. Future perspectives and possible challenges in this emerging field are briefly described. Expert opinion: GO and its derivatives are highly attractive for the application to drug delivery due to their exceptional physiochemical properties and unique planar structure in spite of some existing challenges, such as the reproducibly smart functionalization of GO and the investigation of its long-term toxicology. 2013-09-30T08:29:41Z 2019-12-06T20:13:50Z 2013-09-30T08:29:41Z 2019-12-06T20:13:50Z 2012 2012 Journal Article Pan, Y., Sahoo, N. G., & Li, L. (2012). The application of graphene oxide in drug delivery. Expert opinion on drug delivery, 9(11), 1365-1376. https://hdl.handle.net/10356/99938 http://hdl.handle.net/10220/13748 10.1517/17425247.2012.729575 en Expert opinion on drug delivery
spellingShingle DRNTU::Engineering::Mechanical engineering
Pan, Yongzheng
Sahoo, Nanda Gopal
Li, Lin
The application of graphene oxide in drug delivery
title The application of graphene oxide in drug delivery
title_full The application of graphene oxide in drug delivery
title_fullStr The application of graphene oxide in drug delivery
title_full_unstemmed The application of graphene oxide in drug delivery
title_short The application of graphene oxide in drug delivery
title_sort application of graphene oxide in drug delivery
topic DRNTU::Engineering::Mechanical engineering
url https://hdl.handle.net/10356/99938
http://hdl.handle.net/10220/13748
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