| Summary: | Optimation of CO2laser power intracavity as a radiation source of
photoacoustic spectrometer has been done in the detection ofacetone gas for a
biomarker of diabetes mellitus through human breath.This is indicated by the laser
power stability in 4,5 W and the detection limits as low as (2,3 ± 0,2) ppb. Its
application to detect and measure concentration of acetone gas (C3H6O) through
human breath goes well. The acetone gas concentration for volunteer patients with
diabetes mellitus ranging from 129 ppb to 3872 ppb with average concentration
1685 ppb, while the acetone gas concentration for healthy volunteer ranging from
13 ppb to 139 ppb with average concentration 53 ppb.Then conducted test of two
populations random using the statistical analysis of the t-test with significance
value0,05 and confidence interval 95%.Quantitatively, the results of t-test showed
a highly significant difference between the average acetone gas concentration for
volunteer patients with diabetes mellitus and healthy volunteer.
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