UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI DEFISIENSI BESI PADA ANAK BALITA
Background. Iron deficient is the common cause of anemia worldwide. Most of the children suffer from iron deficient and iron deficiency anemia. Iron deficiency anemia cause great impact to cognitive and motoric development in children until 10 years even though iron therapy has been given. Therefore...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2012
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| _version_ | 1797032644899241984 |
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| author | , WINDY SAUFIA APRIYANTI , Prof. Dr. dr. Sutaryo, Sp.A(K) |
| author_facet | , WINDY SAUFIA APRIYANTI , Prof. Dr. dr. Sutaryo, Sp.A(K) |
| author_sort | , WINDY SAUFIA APRIYANTI |
| collection | UGM |
| description | Background. Iron deficient is the common cause of anemia worldwide. Most of
the children suffer from iron deficient and iron deficiency anemia. Iron deficiency
anemia cause great impact to cognitive and motoric development in children until
10 years even though iron therapy has been given. Therefore, early detection of
iron deficient is highly recommended. Ferritin serum can be used as an alternative
tool in detecting iron deficient.
Objective. To assess the diagnostic value of ferritin serum in detecting iron
deficient among children below five years.
Method. A cross sectional diagnostic test was performed in primary health care at
Yogyakarta and Bantul. The inclusion criteria were children in the age of 6 � 59
months. Children who suffered anemia, infection, inflammation and treated with
iron therapy and ferritin serum >140 ug/L were excluded. The level of serum
receptor transferrin (sTfR) �8,2 mg/L used for gold standard in determining iron
deficient Diagnostic value count from the level of ferritin serum compared to
serum receptor transferrin. Receiver operator curve (ROC) was conducted to
choose cut off point of ferritin serum.
Result. Prevalence of iron deficient was 32,2% (29/90). The highest prevalence
found in the age of 25 � 59 months. Mean hemoglobin level in iron deficient
children were lower than healthy children (11,7±0,5 and 12,2±0,7), mean sTfR
level in iron deficient children were higher than healthy children (9,3±1,1 and
6,2±1,1), there were no significance difference of ferritin serum level between two
groups (p=0,228). Sensitivity, specificity and NDP of ferritin serum were 17%,
93% and 56% respectively. Based on ROC, the new cut off point of ferritin serum
that was be chosen, was 32,4 ug/L with sensitivity 62,1% and specificity 50,8%.
Conclusion. Diagnostic value of ferritin serum was not good enough. Therefore it
wasn�t able to be an ideal indicator in detecting iron deficient among children
below five years. |
| first_indexed | 2024-03-13T22:41:30Z |
| format | Thesis |
| id | oai:generic.eprints.org:100116 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T22:41:30Z |
| publishDate | 2012 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1001162016-03-04T08:49:21Z https://repository.ugm.ac.id/100116/ UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI DEFISIENSI BESI PADA ANAK BALITA , WINDY SAUFIA APRIYANTI , Prof. Dr. dr. Sutaryo, Sp.A(K) ETD Background. Iron deficient is the common cause of anemia worldwide. Most of the children suffer from iron deficient and iron deficiency anemia. Iron deficiency anemia cause great impact to cognitive and motoric development in children until 10 years even though iron therapy has been given. Therefore, early detection of iron deficient is highly recommended. Ferritin serum can be used as an alternative tool in detecting iron deficient. Objective. To assess the diagnostic value of ferritin serum in detecting iron deficient among children below five years. Method. A cross sectional diagnostic test was performed in primary health care at Yogyakarta and Bantul. The inclusion criteria were children in the age of 6 � 59 months. Children who suffered anemia, infection, inflammation and treated with iron therapy and ferritin serum >140 ug/L were excluded. The level of serum receptor transferrin (sTfR) �8,2 mg/L used for gold standard in determining iron deficient Diagnostic value count from the level of ferritin serum compared to serum receptor transferrin. Receiver operator curve (ROC) was conducted to choose cut off point of ferritin serum. Result. Prevalence of iron deficient was 32,2% (29/90). The highest prevalence found in the age of 25 � 59 months. Mean hemoglobin level in iron deficient children were lower than healthy children (11,7±0,5 and 12,2±0,7), mean sTfR level in iron deficient children were higher than healthy children (9,3±1,1 and 6,2±1,1), there were no significance difference of ferritin serum level between two groups (p=0,228). Sensitivity, specificity and NDP of ferritin serum were 17%, 93% and 56% respectively. Based on ROC, the new cut off point of ferritin serum that was be chosen, was 32,4 ug/L with sensitivity 62,1% and specificity 50,8%. Conclusion. Diagnostic value of ferritin serum was not good enough. Therefore it wasn�t able to be an ideal indicator in detecting iron deficient among children below five years. [Yogyakarta] : Universitas Gadjah Mada 2012 Thesis NonPeerReviewed , WINDY SAUFIA APRIYANTI and , Prof. Dr. dr. Sutaryo, Sp.A(K) (2012) UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI DEFISIENSI BESI PADA ANAK BALITA. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=56522 |
| spellingShingle | ETD , WINDY SAUFIA APRIYANTI , Prof. Dr. dr. Sutaryo, Sp.A(K) UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI DEFISIENSI BESI PADA ANAK BALITA |
| title | UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI
DEFISIENSI BESI PADA ANAK BALITA |
| title_full | UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI
DEFISIENSI BESI PADA ANAK BALITA |
| title_fullStr | UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI
DEFISIENSI BESI PADA ANAK BALITA |
| title_full_unstemmed | UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI
DEFISIENSI BESI PADA ANAK BALITA |
| title_short | UJI DIAGNOSTIK FERITIN SERUM UNTUK DETEKSI
DEFISIENSI BESI PADA ANAK BALITA |
| title_sort | uji diagnostik feritin serum untuk deteksi defisiensi besi pada anak balita |
| topic | ETD |
| work_keys_str_mv | AT windysaufiaapriyanti ujidiagnostikferitinserumuntukdeteksidefisiensibesipadaanakbalita AT profdrdrsutaryospak ujidiagnostikferitinserumuntukdeteksidefisiensibesipadaanakbalita |