KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI

Malnutrition is a common condition in liver cirrhotic patients. Leptin was regulated physiologically body wieght by suppressing appetite and increasing energy expenditure. Leptin is higher in female than male. Several studies have shown correlation between leptin with metabolic factors like body mas...

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Main Authors: , SITI MARYANI, , dr.Neneng Ratnasari, SpPD-KGEH
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2012
Subjects:
ETD
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author , SITI MARYANI
, dr.Neneng Ratnasari, SpPD-KGEH,
author_facet , SITI MARYANI
, dr.Neneng Ratnasari, SpPD-KGEH,
author_sort , SITI MARYANI
collection UGM
description Malnutrition is a common condition in liver cirrhotic patients. Leptin was regulated physiologically body wieght by suppressing appetite and increasing energy expenditure. Leptin is higher in female than male. Several studies have shown correlation between leptin with metabolic factors like body mass index and lipid profile in cirrhotic patients. In this study, we investigate the correlation between leptin levels with lipid profile and free fatty acid in male liver cirrhotic patients. The hypothesis was there is a correlation between leptin level with lipid profile and free fatty acid in male liver cirrhotic patients. The design is cross sectional study. This study was conducted at Gastroenterohepatology clinic and Interna Ward at Sardjito General Hospital, Yogyakarta. Inclusion criterias were patients with liver cirrhosis � 18 years old , male, Child-Pugh classification B and C, and obtained informed consent. Exclusion criterias were liver cirrhotic patients with comorbidity chronic kidney disease, chronic heart failure, diabetic, cancer, infection/septic, pregnancy, breast feeding, and steroid user. Data collecting was done by anamnesis, physical examination, abdominal ultrasonography examination, and chemical blood test. Statistic methods was used correlation analysis with Pearson test. The result of this study was shown negative correlations that statistically non significant between leptin level and total cholesterol, HDL and triglyseride in male liver cirrhotic patients with correlation coefficient (cholesterol: r= -0,052
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spelling oai:generic.eprints.org:1001292016-03-04T08:48:45Z https://repository.ugm.ac.id/100129/ KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI , SITI MARYANI , dr.Neneng Ratnasari, SpPD-KGEH, ETD Malnutrition is a common condition in liver cirrhotic patients. Leptin was regulated physiologically body wieght by suppressing appetite and increasing energy expenditure. Leptin is higher in female than male. Several studies have shown correlation between leptin with metabolic factors like body mass index and lipid profile in cirrhotic patients. In this study, we investigate the correlation between leptin levels with lipid profile and free fatty acid in male liver cirrhotic patients. The hypothesis was there is a correlation between leptin level with lipid profile and free fatty acid in male liver cirrhotic patients. The design is cross sectional study. This study was conducted at Gastroenterohepatology clinic and Interna Ward at Sardjito General Hospital, Yogyakarta. Inclusion criterias were patients with liver cirrhosis � 18 years old , male, Child-Pugh classification B and C, and obtained informed consent. Exclusion criterias were liver cirrhotic patients with comorbidity chronic kidney disease, chronic heart failure, diabetic, cancer, infection/septic, pregnancy, breast feeding, and steroid user. Data collecting was done by anamnesis, physical examination, abdominal ultrasonography examination, and chemical blood test. Statistic methods was used correlation analysis with Pearson test. The result of this study was shown negative correlations that statistically non significant between leptin level and total cholesterol, HDL and triglyseride in male liver cirrhotic patients with correlation coefficient (cholesterol: r= -0,052 [Yogyakarta] : Universitas Gadjah Mada 2012 Thesis NonPeerReviewed , SITI MARYANI and , dr.Neneng Ratnasari, SpPD-KGEH, (2012) KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=56175
spellingShingle ETD
, SITI MARYANI
, dr.Neneng Ratnasari, SpPD-KGEH,
KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI
title KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI
title_full KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI
title_fullStr KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI
title_full_unstemmed KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI
title_short KORELASI ANTARA KADAR LEPTIN DENGAN PROFIL LIPID DAN FREE FATTY ACID PADA SIROSIS HATI
title_sort korelasi antara kadar leptin dengan profil lipid dan free fatty acid pada sirosis hati
topic ETD
work_keys_str_mv AT sitimaryani korelasiantarakadarleptindenganprofillipiddanfreefattyacidpadasirosishati
AT drnenengratnasarisppdkgeh korelasiantarakadarleptindenganprofillipiddanfreefattyacidpadasirosishati