| Summary: | Background : Antibiotic Associated Diarrhea (AAD) is unexplained diarrhea
occurring after starting antibiotics. In 20% AAD is cause by C.difficile. Diarrhea is
the most effect after antibiotics consumed and altering the gut mucosa membrane also
the composition of the normal bacterial flora with overgrowth the pathogen bacteria.
At RS.dr. Sardjito in 2006, Damayanti W found that prevalence of AAD 17.4%
mostly caused by ampicillin combined with cefotaxim intravenous.
Objective: to find out the other risk factors contribute increasing AAD in pediatrics
ward in RS.Dr.Sardjito, in order to decrease duration of hospitalization, psychological
burden, cost and also mortality and morbidity.
Methods: we using case control study in 118 pediatrics hospitalized patient in
RSUP.dr.Sardjito, Yogyakarta meet the criteria. We used secondary data from
medical record between Januari 2010 to Desember 2010. Bivariate and logistic
regresi are used to analyzing data.
Results: from univarite analyze we found that enteral tube was the only significant
risk factor to increasing AAD, OR 3.52 (p < 0.05, CI 95% 1.622 � 7.664) and also
from logistic regresi OR 4.5 (p = 0.014, CI 95% 1.36 � 15.17). The others variable
from characteristic data such as age, nutritional status, and kind antibiotics also
contribute in AAD. Nevertheless, we cannot found the biological plausibility about
enteral feeding itself increasing AAD.
Conclusion: enteral feeding is the only risk factors that significantly increasing AAD
in hospitalized pediatric patients, but the biological plausibility about this two factors
most be confirm.
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