| Summary: | Curcumin is the major yellow pigment of curcuma. Recently, it has been
reported that curcumin exhibit numerous pharmacological activities, thus makes
interesting to study curcumin in preclinical and clinical research. Therefore, it is
necessary to validate bioanalytical method associated with the use of curcumin in
clinical laboratories. This study was done in order to obtain optimum conditions and
the High Performance Liquid Chromatography (HPLC) method validity, with a C18
column and UV-vis detector, using the SPE HLB, in the determination of curcumin
in human plasma.
In this study has been used Shim-pack (Shimadzu) VP-ODS column (150 x
4,6 mm
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