HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN KARAKTERISTIK KLINIKOPATOLOGIK KARSINOMA KOLOREKTAL
Over expression of p53 protein has been documented in human malignancies and shown to be associated with poor prognosis. hMLHI is a mismatch repair gene usually found in hereditary nonpolyposis and colorectal cancer. However, the relation between p53-, hMLHI expression and clinicopathological charac...
| Main Authors: | , |
|---|---|
| Format: | Thesis |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2013
|
| Subjects: |
| _version_ | 1797032873526558720 |
|---|---|
| author | , PIERI KUMALADEWI , Prof. Dr. dr. Soeripto, SpPA(K) |
| author_facet | , PIERI KUMALADEWI , Prof. Dr. dr. Soeripto, SpPA(K) |
| author_sort | , PIERI KUMALADEWI |
| collection | UGM |
| description | Over expression of p53 protein has been documented in human malignancies
and shown to be associated with poor prognosis. hMLHI is a mismatch repair gene usually found in hereditary nonpolyposis and colorectal cancer. However, the relation between p53-, hMLHI expression and clinicopathological characteristic of colorectal carcinoma is still controversial.
Aim: To analyse the correlation of p53 and hMLHI expression in colorectal carcinoma cases with several clinicopathological characteristics using immunohistochemistry.
Method : 45 paraffin-preserved adenocarcinoma colorectal cases were collected from
Sardjito Hospital, Bethesda Hospital and Panti Rapih Hospital. The expression of p53 was detected using clone of DO-7 |
| first_indexed | 2024-03-13T22:45:18Z |
| format | Thesis |
| id | oai:generic.eprints.org:118059 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T22:45:18Z |
| publishDate | 2013 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1180592016-03-04T08:41:42Z https://repository.ugm.ac.id/118059/ HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN KARAKTERISTIK KLINIKOPATOLOGIK KARSINOMA KOLOREKTAL , PIERI KUMALADEWI , Prof. Dr. dr. Soeripto, SpPA(K) ETD Over expression of p53 protein has been documented in human malignancies and shown to be associated with poor prognosis. hMLHI is a mismatch repair gene usually found in hereditary nonpolyposis and colorectal cancer. However, the relation between p53-, hMLHI expression and clinicopathological characteristic of colorectal carcinoma is still controversial. Aim: To analyse the correlation of p53 and hMLHI expression in colorectal carcinoma cases with several clinicopathological characteristics using immunohistochemistry. Method : 45 paraffin-preserved adenocarcinoma colorectal cases were collected from Sardjito Hospital, Bethesda Hospital and Panti Rapih Hospital. The expression of p53 was detected using clone of DO-7 [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , PIERI KUMALADEWI and , Prof. Dr. dr. Soeripto, SpPA(K) (2013) HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN KARAKTERISTIK KLINIKOPATOLOGIK KARSINOMA KOLOREKTAL. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=51490 |
| spellingShingle | ETD , PIERI KUMALADEWI , Prof. Dr. dr. Soeripto, SpPA(K) HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN KARAKTERISTIK KLINIKOPATOLOGIK KARSINOMA KOLOREKTAL |
| title | HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN
KARAKTERISTIK KLINIKOPATOLOGIK
KARSINOMA KOLOREKTAL |
| title_full | HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN
KARAKTERISTIK KLINIKOPATOLOGIK
KARSINOMA KOLOREKTAL |
| title_fullStr | HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN
KARAKTERISTIK KLINIKOPATOLOGIK
KARSINOMA KOLOREKTAL |
| title_full_unstemmed | HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN
KARAKTERISTIK KLINIKOPATOLOGIK
KARSINOMA KOLOREKTAL |
| title_short | HUBUNGAN EKSPRESI p53 DAN hMLH1 DENGAN
KARAKTERISTIK KLINIKOPATOLOGIK
KARSINOMA KOLOREKTAL |
| title_sort | hubungan ekspresi p53 dan hmlh1 dengan karakteristik klinikopatologik karsinoma kolorektal |
| topic | ETD |
| work_keys_str_mv | AT pierikumaladewi hubunganekspresip53danhmlh1dengankarakteristikklinikopatologikkarsinomakolorektal AT profdrdrsoeriptosppak hubunganekspresip53danhmlh1dengankarakteristikklinikopatologikkarsinomakolorektal |