PERBANDINGAN KADAR MALONDIALDEHID SERUM PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS Studi pada Populasi Pria di Yogyakarta
Acne is an inflamative chronic skin disease which has multifactorial pathogenesis such as sebaceous hyperplasia, follicular hiperkeratinization, hipercolonization of Propionibacterium acnes, and inflammation. Oxidative stress especially lipid peroxidation in purpose is one trigger inflammation in ac...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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| _version_ | 1826046070750183424 |
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| author | , Aprilina Dwi Sulistyowati , dr. Kristiana Etnawati, MPH, Sp.KK(K) |
| author_facet | , Aprilina Dwi Sulistyowati , dr. Kristiana Etnawati, MPH, Sp.KK(K) |
| author_sort | , Aprilina Dwi Sulistyowati |
| collection | UGM |
| description | Acne is an inflamative chronic skin disease which has multifactorial
pathogenesis such as sebaceous hyperplasia, follicular hiperkeratinization,
hipercolonization of Propionibacterium acnes, and inflammation. Oxidative
stress especially lipid peroxidation in purpose is one trigger inflammation in acne
vulgaris. Oxidative stress is also influenced by environmental factors and
ultraviolet (UV) light. The UV radiation in Yogyakarta is relatively higher
compare in other region. Effect of high UV will increase lipid peroxidation in the
skin so that the malondialdehyde (MDA) as the outcome of lipid peroxidation
will be increased and eventually lead to inflammation in acne. This research was
conducted to compare the levels of serum MDA in various degrees of severity of
acne vulgaris in Yogyakarta.
An observasional, descriptive, and cross sectional study was conducted
in Yogyakarta with a consecutive sampling method to achieve 60 male acne
subject. The combined acne severity classification (CASC) method is used to
determine the severity of acne. Statistical analysis uses one way analysis test of
variance and Spearman's rho correlation test with a significance value of p<0.05.
Sixty male acne subjects were divided into 3 groups, namely mild,
moderate, and severe acne. Each of these group consists of 20 subjects. Mild acne
showed MDA levels lower than moderate (p= 0.002) and severe acne (p=0.000)
and moderate acne also lower than severe acne (p=0.000). There were strong
positive correlation between MDA serum with acne lesion total count (p=0.000 |
| first_indexed | 2024-03-13T22:47:29Z |
| format | Thesis |
| id | oai:generic.eprints.org:118726 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T22:47:29Z |
| publishDate | 2013 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1187262016-03-04T08:26:48Z https://repository.ugm.ac.id/118726/ PERBANDINGAN KADAR MALONDIALDEHID SERUM PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS Studi pada Populasi Pria di Yogyakarta , Aprilina Dwi Sulistyowati , dr. Kristiana Etnawati, MPH, Sp.KK(K) ETD Acne is an inflamative chronic skin disease which has multifactorial pathogenesis such as sebaceous hyperplasia, follicular hiperkeratinization, hipercolonization of Propionibacterium acnes, and inflammation. Oxidative stress especially lipid peroxidation in purpose is one trigger inflammation in acne vulgaris. Oxidative stress is also influenced by environmental factors and ultraviolet (UV) light. The UV radiation in Yogyakarta is relatively higher compare in other region. Effect of high UV will increase lipid peroxidation in the skin so that the malondialdehyde (MDA) as the outcome of lipid peroxidation will be increased and eventually lead to inflammation in acne. This research was conducted to compare the levels of serum MDA in various degrees of severity of acne vulgaris in Yogyakarta. An observasional, descriptive, and cross sectional study was conducted in Yogyakarta with a consecutive sampling method to achieve 60 male acne subject. The combined acne severity classification (CASC) method is used to determine the severity of acne. Statistical analysis uses one way analysis test of variance and Spearman's rho correlation test with a significance value of p<0.05. Sixty male acne subjects were divided into 3 groups, namely mild, moderate, and severe acne. Each of these group consists of 20 subjects. Mild acne showed MDA levels lower than moderate (p= 0.002) and severe acne (p=0.000) and moderate acne also lower than severe acne (p=0.000). There were strong positive correlation between MDA serum with acne lesion total count (p=0.000 [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , Aprilina Dwi Sulistyowati and , dr. Kristiana Etnawati, MPH, Sp.KK(K) (2013) PERBANDINGAN KADAR MALONDIALDEHID SERUM PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS Studi pada Populasi Pria di Yogyakarta. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=58700 |
| spellingShingle | ETD , Aprilina Dwi Sulistyowati , dr. Kristiana Etnawati, MPH, Sp.KK(K) PERBANDINGAN KADAR MALONDIALDEHID SERUM PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS Studi pada Populasi Pria di Yogyakarta |
| title | PERBANDINGAN KADAR MALONDIALDEHID SERUM
PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS
Studi pada Populasi Pria di Yogyakarta |
| title_full | PERBANDINGAN KADAR MALONDIALDEHID SERUM
PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS
Studi pada Populasi Pria di Yogyakarta |
| title_fullStr | PERBANDINGAN KADAR MALONDIALDEHID SERUM
PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS
Studi pada Populasi Pria di Yogyakarta |
| title_full_unstemmed | PERBANDINGAN KADAR MALONDIALDEHID SERUM
PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS
Studi pada Populasi Pria di Yogyakarta |
| title_short | PERBANDINGAN KADAR MALONDIALDEHID SERUM
PADA BERBAGAI DERAJAT KEPARAHAN AKNE VULGARIS
Studi pada Populasi Pria di Yogyakarta |
| title_sort | perbandingan kadar malondialdehid serum pada berbagai derajat keparahan akne vulgaris studi pada populasi pria di yogyakarta |
| topic | ETD |
| work_keys_str_mv | AT aprilinadwisulistyowati perbandingankadarmalondialdehidserumpadaberbagaiderajatkeparahanaknevulgarisstudipadapopulasipriadiyogyakarta AT drkristianaetnawatimphspkkk perbandingankadarmalondialdehidserumpadaberbagaiderajatkeparahanaknevulgarisstudipadapopulasipriadiyogyakarta |