HUBUNGAN Procollagen type I N-terminal propeptide SERUM DENGAN BONE MINERAL DENSITY PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE
Osteoporosis is a metabolic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Perimenopause and postmenopause women had greater risk to suffering osteoporosis as a result o...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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| author | , Arlan Prabowo , dr. Windarwati, Sp.PK(K) |
| author_facet | , Arlan Prabowo , dr. Windarwati, Sp.PK(K) |
| author_sort | , Arlan Prabowo |
| collection | UGM |
| description | Osteoporosis is a metabolic skeletal disease characterized by low bone
mass and microarchitectural deterioration of bone tissue, with a consequent
increase in bone fragility and susceptibility to fracture. Perimenopause and
postmenopause women had greater risk to suffering osteoporosis as a result of
estrogen deficiency. The dual energy X-ray absorptiometry (DEXA) of lumbar
spine and pelvic bone is a gold standart for diagnose osteoporosis by measure
bone mineral density (BMD), but had limited availability in hospitals.
The one of biochemical markers of bone turnover to measure bone mass
deterioration is procollagen type I N-terminal propeptide (PINP). The PINP has
better diagnostic validity than other biochemical markers of bone turnover
because of temperature stability and not affected by elongation time of transport
and storage.The aim of this study is to find out the relationship between the PINP
serum level and deterioration of bone mass density which measured by DEXA
method in perimenopause and postmenopause women.
This is a cross-sectional study. The subject are women more than 45 years
old, both perimenopause and postmenopause. The PINP serum measured by
electrochemiluminescence immunoassay method. The DEXA method is used for
measure BMD.
A significant correlation between the PINP serum�s level and status of
bone mineral density will run the chance of use of PINP as a cheaper biochemical
marker of bone turnover in osteoporosis management. |
| first_indexed | 2024-03-13T22:48:04Z |
| format | Thesis |
| id | oai:generic.eprints.org:118920 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T22:48:04Z |
| publishDate | 2013 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1189202016-03-04T08:27:07Z https://repository.ugm.ac.id/118920/ HUBUNGAN Procollagen type I N-terminal propeptide SERUM DENGAN BONE MINERAL DENSITY PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE , Arlan Prabowo , dr. Windarwati, Sp.PK(K) ETD Osteoporosis is a metabolic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Perimenopause and postmenopause women had greater risk to suffering osteoporosis as a result of estrogen deficiency. The dual energy X-ray absorptiometry (DEXA) of lumbar spine and pelvic bone is a gold standart for diagnose osteoporosis by measure bone mineral density (BMD), but had limited availability in hospitals. The one of biochemical markers of bone turnover to measure bone mass deterioration is procollagen type I N-terminal propeptide (PINP). The PINP has better diagnostic validity than other biochemical markers of bone turnover because of temperature stability and not affected by elongation time of transport and storage.The aim of this study is to find out the relationship between the PINP serum level and deterioration of bone mass density which measured by DEXA method in perimenopause and postmenopause women. This is a cross-sectional study. The subject are women more than 45 years old, both perimenopause and postmenopause. The PINP serum measured by electrochemiluminescence immunoassay method. The DEXA method is used for measure BMD. A significant correlation between the PINP serum�s level and status of bone mineral density will run the chance of use of PINP as a cheaper biochemical marker of bone turnover in osteoporosis management. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , Arlan Prabowo and , dr. Windarwati, Sp.PK(K) (2013) HUBUNGAN Procollagen type I N-terminal propeptide SERUM DENGAN BONE MINERAL DENSITY PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=58898 |
| spellingShingle | ETD , Arlan Prabowo , dr. Windarwati, Sp.PK(K) HUBUNGAN Procollagen type I N-terminal propeptide SERUM DENGAN BONE MINERAL DENSITY PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE |
| title | HUBUNGAN Procollagen type I N-terminal propeptide SERUM
DENGAN BONE MINERAL DENSITY
PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE |
| title_full | HUBUNGAN Procollagen type I N-terminal propeptide SERUM
DENGAN BONE MINERAL DENSITY
PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE |
| title_fullStr | HUBUNGAN Procollagen type I N-terminal propeptide SERUM
DENGAN BONE MINERAL DENSITY
PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE |
| title_full_unstemmed | HUBUNGAN Procollagen type I N-terminal propeptide SERUM
DENGAN BONE MINERAL DENSITY
PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE |
| title_short | HUBUNGAN Procollagen type I N-terminal propeptide SERUM
DENGAN BONE MINERAL DENSITY
PADA WANITA USIA PERIMENOPAUSE DAN SETELAH MENOPAUSE |
| title_sort | hubungan procollagen type i n terminal propeptide serum dengan bone mineral density pada wanita usia perimenopause dan setelah menopause |
| topic | ETD |
| work_keys_str_mv | AT arlanprabowo hubunganprocollagentypeinterminalpropeptideserumdenganbonemineraldensitypadawanitausiaperimenopausedansetelahmenopause AT drwindarwatisppkk hubunganprocollagentypeinterminalpropeptideserumdenganbonemineraldensitypadawanitausiaperimenopausedansetelahmenopause |