| Summary: | Background. The decline of estrogen level causes various skin changes which include fibroblast, as well as the thickness of epidermis and dermis. Physical exercise is believed to increase the level of estrogen and give positive impacts on skin. Its mechanism is often associated with the increase of extragonadal aromatization and estrogen serum, the activation of IGF, and the expression of
estrogen receptor. Objective. This research aims at examining the increase of fibroblast amount, and the thickness of epidermis and dermis after ovariectomy and in rats given also
physical exercise by measuring the levels of estrogen β receptor (ER β) in skin and estrogen serum. Method. The study was an experiment with post test group design only. This research uses 8 female Sprague dawley rats aged 3 months which is divided into
several groups. Group 1 consists of ovariectomized rats but given no physical
exercise
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