PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI

Background. Valproic acid is one of the AED commonly prescribed to control epileptic seizure. Cognitive and behavioral disorder have been associated with barbiturate and benzodiazepine, while their association with valproic acid is still a matter of debate. Valproic acid effect on academic performan...

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Main Authors: , Andrianto Selohandono, , Prof. dr. Harsono, Sp.S.(K)
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2013
Subjects:
ETD
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author , Andrianto Selohandono
, Prof. dr. Harsono, Sp.S.(K)
author_facet , Andrianto Selohandono
, Prof. dr. Harsono, Sp.S.(K)
author_sort , Andrianto Selohandono
collection UGM
description Background. Valproic acid is one of the AED commonly prescribed to control epileptic seizure. Cognitive and behavioral disorder have been associated with barbiturate and benzodiazepine, while their association with valproic acid is still a matter of debate. Valproic acid effect on academic performance in children with epilepsy is still largely unknown. Method. This is a case control study. Pediatric epileptic patient between 7-12 years old were recruited as subjects. Children who assigned with valproic acid were compared with children who received any non-valproic AED as control group. Academic performance were assessed from children report card, particularly their Indonesian language and math score compared their class average score. Result. A Total of 54 subjects were recruited for study, 22 subjects indicated worse academic performance in Indonesian language, while 30 subjects indicated worse academic performance in math. Generalized type seizure and the occurence of seizure in the last month were significantly and independently associated with worse academic performance. While, valproic acid only had significant associated with worse math performance in univariate analysis
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spelling oai:generic.eprints.org:1194132016-03-04T08:26:30Z https://repository.ugm.ac.id/119413/ PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI , Andrianto Selohandono , Prof. dr. Harsono, Sp.S.(K) ETD Background. Valproic acid is one of the AED commonly prescribed to control epileptic seizure. Cognitive and behavioral disorder have been associated with barbiturate and benzodiazepine, while their association with valproic acid is still a matter of debate. Valproic acid effect on academic performance in children with epilepsy is still largely unknown. Method. This is a case control study. Pediatric epileptic patient between 7-12 years old were recruited as subjects. Children who assigned with valproic acid were compared with children who received any non-valproic AED as control group. Academic performance were assessed from children report card, particularly their Indonesian language and math score compared their class average score. Result. A Total of 54 subjects were recruited for study, 22 subjects indicated worse academic performance in Indonesian language, while 30 subjects indicated worse academic performance in math. Generalized type seizure and the occurence of seizure in the last month were significantly and independently associated with worse academic performance. While, valproic acid only had significant associated with worse math performance in univariate analysis [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , Andrianto Selohandono and , Prof. dr. Harsono, Sp.S.(K) (2013) PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=59412
spellingShingle ETD
, Andrianto Selohandono
, Prof. dr. Harsono, Sp.S.(K)
PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI
title PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI
title_full PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI
title_fullStr PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI
title_full_unstemmed PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI
title_short PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI
title_sort pengaruh asam valproat terhadap prestasi belajar anak dengan epilepsi
topic ETD
work_keys_str_mv AT andriantoselohandono pengaruhasamvalproatterhadapprestasibelajaranakdenganepilepsi
AT profdrharsonospsk pengaruhasamvalproatterhadapprestasibelajaranakdenganepilepsi