PENGARUH KADAR PROPILEN GLIKOL, TWEEN 80 DAN BESAR ARUS IONTOFORESIS TERHADAP TRANSPOR TRANSDERMAL PROMETAZIN HCL SECARA IN VITRO
Promethazine HCl undergoes extensive hepatic first-pass metabolism following oral administration resulted in a low bioavailability at around 25%. Oral absorption is often interrupted by nausea and vomiting, so the bioavalability is low and morning sickness is not treated verry well. The purposes of...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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