VISKOSITAS PLASMA SEBAGAI FAKTOR RISIKO GLAUKOMA NORMOTENSI

A case-control study of plasma viscosity as a risk factor for normotension glaucoma (NTG) to determine the contribution of plasma hyperviscosity, as one of NTG risk factors has been conducted. The subjects were divided into groups of NTG and the control group, each 30 persons with gender representat...

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Bibliographic Details
Main Authors: , Erin Arsianti, , Dr. Retno Ekantini, SpM(K), M.Kes
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2013
Subjects:
ETD
Description
Summary:A case-control study of plasma viscosity as a risk factor for normotension glaucoma (NTG) to determine the contribution of plasma hyperviscosity, as one of NTG risk factors has been conducted. The subjects were divided into groups of NTG and the control group, each 30 persons with gender representation at the age of 18-40 years old. Plasma viscosity, fibrinogen, albumin, globulin of every individual were measured. The collected data were analyzed by multivariate analysis using logistic regression. Fibrinogen concentration of NTG patients were not significantly different from the control (OR 1.157, 95% CI 0.40 to 3.34, p = 0.787). Albumin concentration of NTG patients was also not different from the controls (OR 2.59, 95% CI 0.91 to 7.34, p = 0.071). Although globulin concentrations of NTG patients were significantly different from the control (OR 7.25, 95% CI 0.82 to 64.42, p = 0.044), statistically it was not enough to conclude globulin as NTG risk factor. NTG patients have higher and significantly different plasma viscosity values than the control (OR 8.61, 95% CI 2.56 to 29.1, p = 0.001). In conclusion, plasma viscosity proved to be one of the risk factors of NTG.