KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN
Background: Early detection of iron deficiency before anemia in early children especially beyond 6-59 months become important due to its impact to permanent neurocognitive development disorder. Bone marrow aspiration with Prussian blue staining was not routinely done because of the invasive procedur...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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| author | , dr. Fajar Diah Tri Kusumastuti , Prof. Dr. dr. Sutaryo, Sp.A(K) |
| author_facet | , dr. Fajar Diah Tri Kusumastuti , Prof. Dr. dr. Sutaryo, Sp.A(K) |
| author_sort | , dr. Fajar Diah Tri Kusumastuti |
| collection | UGM |
| description | Background: Early detection of iron deficiency before anemia in early children
especially beyond 6-59 months become important due to its impact to permanent
neurocognitive development disorder. Bone marrow aspiration with Prussian blue
staining was not routinely done because of the invasive procedure. Hemoglobin is
unsensitive tool for iron deficiency without anemia and serum ferritin influenced
by infection and inflammation. Soluble transferrrin receptors (sTfR) is a sensitive
marker for detecting iron deficiency state but is not used widely in daily practice.
Objective: to determine the correlation between hemoglobin level, serum ferritin,
and soluble transferrin receptor in early children 6-59 months.
Methods: This cross sectional study was performed in 6-59 months old children
who visited POSYANDU in Yogyakarta and Bantul districs that choosen by
cluster sampling. Anamnesis, anthropometric and physical examination was
performed. Inclusion criteria were health children appropiate with anamnesis and
examination results. Children who received iron supplementation we excluded.
After fulfilled the informed consent, amount subjects are 85 children. After that,
blood sample was collected to examined hemoglobin, serum ferritin, and soluble
transferrin receptor level.
Results: Spearman correlation test showed a significant correlation between
hemoglobin level and serum ferritin level and also between hemoglobin level and
sTfR with coefficient correlation respectively r= -0,220 (p=0,043), r= -0,317
(p=0,003). Coefficient correlation between serum feritin level and sTfR was r=-
0,033 (p=0,767). Statistically, the correlation is not significant.
Conclusion: The increase level of hemoglobin will correlate with the decrease
level of serum ferritin and sTfR. Meanwhile, the increase level of serum ferritin
will correlate with the decrease level of sTfR. |
| first_indexed | 2024-03-13T22:51:08Z |
| format | Thesis |
| id | oai:generic.eprints.org:119902 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T22:51:08Z |
| publishDate | 2013 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1199022016-03-04T08:44:59Z https://repository.ugm.ac.id/119902/ KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN , dr. Fajar Diah Tri Kusumastuti , Prof. Dr. dr. Sutaryo, Sp.A(K) ETD Background: Early detection of iron deficiency before anemia in early children especially beyond 6-59 months become important due to its impact to permanent neurocognitive development disorder. Bone marrow aspiration with Prussian blue staining was not routinely done because of the invasive procedure. Hemoglobin is unsensitive tool for iron deficiency without anemia and serum ferritin influenced by infection and inflammation. Soluble transferrrin receptors (sTfR) is a sensitive marker for detecting iron deficiency state but is not used widely in daily practice. Objective: to determine the correlation between hemoglobin level, serum ferritin, and soluble transferrin receptor in early children 6-59 months. Methods: This cross sectional study was performed in 6-59 months old children who visited POSYANDU in Yogyakarta and Bantul districs that choosen by cluster sampling. Anamnesis, anthropometric and physical examination was performed. Inclusion criteria were health children appropiate with anamnesis and examination results. Children who received iron supplementation we excluded. After fulfilled the informed consent, amount subjects are 85 children. After that, blood sample was collected to examined hemoglobin, serum ferritin, and soluble transferrin receptor level. Results: Spearman correlation test showed a significant correlation between hemoglobin level and serum ferritin level and also between hemoglobin level and sTfR with coefficient correlation respectively r= -0,220 (p=0,043), r= -0,317 (p=0,003). Coefficient correlation between serum feritin level and sTfR was r=- 0,033 (p=0,767). Statistically, the correlation is not significant. Conclusion: The increase level of hemoglobin will correlate with the decrease level of serum ferritin and sTfR. Meanwhile, the increase level of serum ferritin will correlate with the decrease level of sTfR. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , dr. Fajar Diah Tri Kusumastuti and , Prof. Dr. dr. Sutaryo, Sp.A(K) (2013) KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=59908 |
| spellingShingle | ETD , dr. Fajar Diah Tri Kusumastuti , Prof. Dr. dr. Sutaryo, Sp.A(K) KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN |
| title | KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN
SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN |
| title_full | KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN
SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN |
| title_fullStr | KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN
SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN |
| title_full_unstemmed | KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN
SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN |
| title_short | KORELASI ANTARA KADAR HEMOGLOBIN, FERITIN SERUM, DAN
SOLUBLE TRANSFERRIN RECEPTOR PADA ANAK USIA 6-59 BULAN |
| title_sort | korelasi antara kadar hemoglobin feritin serum dan soluble transferrin receptor pada anak usia 6 59 bulan |
| topic | ETD |
| work_keys_str_mv | AT drfajardiahtrikusumastuti korelasiantarakadarhemoglobinferitinserumdansolubletransferrinreceptorpadaanakusia659bulan AT profdrdrsutaryospak korelasiantarakadarhemoglobinferitinserumdansolubletransferrinreceptorpadaanakusia659bulan |