HUBUNGAN PSORIASIS VULGARIS DAN TUMOR NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK
Psoriasis vulgaris is chronic inflammatoryskin disease which mediated by T cell and proinflammatory cytokines. Proinflammatory cytokines especially TNF-α and IL-6 exert systemic effects on insulin resistance. Insulin resistance is basic pathophysiology of metabolic syndrome. Metabolic syndrome is t...
Main Authors: | , |
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Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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author | , Yuni Lidya , Prof. Dr.dr. Hardyanto Soebono, SpKK(K), |
author_facet | , Yuni Lidya , Prof. Dr.dr. Hardyanto Soebono, SpKK(K), |
author_sort | , Yuni Lidya |
collection | UGM |
description | Psoriasis vulgaris is chronic inflammatoryskin disease which mediated by
T cell and proinflammatory cytokines. Proinflammatory cytokines especially
TNF-α and IL-6 exert systemic effects on insulin resistance. Insulin resistance is
basic pathophysiology of metabolic syndrome. Metabolic syndrome is the risk of
individual cardiometabolic diseasewhich include abdominal obesity,
dyslipidemia, hypertension and elevated blood glucose.
The objective of this study was to investigate the association between
psoriasis vulgaris and metabolic syndrome. A cross-sectional study was done
among 40 psoriasis vulgaris patients and 40 non psoriatic healthy subjects
visiting outpatient Department of Dermatology and Venereology clinic Dr.
Sardjito hospital, Yogyakarta. Blood pressure, fasting bood glucose, HDL
cholesterol, waist circumference, triglycerides and TNF-α were examined.
Metabolic syndrome was found in 35% psoriatic patients compared to 15
% in non-psoriatic patients(RR 2,33 |
first_indexed | 2024-03-13T22:51:09Z |
format | Thesis |
id | oai:generic.eprints.org:119909 |
institution | Universiti Gadjah Mada |
last_indexed | 2024-03-13T22:51:09Z |
publishDate | 2013 |
publisher | [Yogyakarta] : Universitas Gadjah Mada |
record_format | dspace |
spelling | oai:generic.eprints.org:1199092016-03-04T08:44:51Z https://repository.ugm.ac.id/119909/ HUBUNGAN PSORIASIS VULGARIS DAN TUMOR NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK , Yuni Lidya , Prof. Dr.dr. Hardyanto Soebono, SpKK(K), ETD Psoriasis vulgaris is chronic inflammatoryskin disease which mediated by T cell and proinflammatory cytokines. Proinflammatory cytokines especially TNF-α and IL-6 exert systemic effects on insulin resistance. Insulin resistance is basic pathophysiology of metabolic syndrome. Metabolic syndrome is the risk of individual cardiometabolic diseasewhich include abdominal obesity, dyslipidemia, hypertension and elevated blood glucose. The objective of this study was to investigate the association between psoriasis vulgaris and metabolic syndrome. A cross-sectional study was done among 40 psoriasis vulgaris patients and 40 non psoriatic healthy subjects visiting outpatient Department of Dermatology and Venereology clinic Dr. Sardjito hospital, Yogyakarta. Blood pressure, fasting bood glucose, HDL cholesterol, waist circumference, triglycerides and TNF-α were examined. Metabolic syndrome was found in 35% psoriatic patients compared to 15 % in non-psoriatic patients(RR 2,33 [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , Yuni Lidya and , Prof. Dr.dr. Hardyanto Soebono, SpKK(K), (2013) HUBUNGAN PSORIASIS VULGARIS DAN TUMOR NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=59915 |
spellingShingle | ETD , Yuni Lidya , Prof. Dr.dr. Hardyanto Soebono, SpKK(K), HUBUNGAN PSORIASIS VULGARIS DAN TUMOR NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK |
title | HUBUNGAN PSORIASIS VULGARIS DAN TUMOR
NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK |
title_full | HUBUNGAN PSORIASIS VULGARIS DAN TUMOR
NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK |
title_fullStr | HUBUNGAN PSORIASIS VULGARIS DAN TUMOR
NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK |
title_full_unstemmed | HUBUNGAN PSORIASIS VULGARIS DAN TUMOR
NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK |
title_short | HUBUNGAN PSORIASIS VULGARIS DAN TUMOR
NECROSIS FACTOR-α DENGAN SINDROMMETABOLIK |
title_sort | hubungan psoriasis vulgaris dan tumor necrosis factor i dengan sindrommetabolik |
topic | ETD |
work_keys_str_mv | AT yunilidya hubunganpsoriasisvulgarisdantumornecrosisfactoridengansindrommetabolik AT profdrdrhardyantosoebonospkkk hubunganpsoriasisvulgarisdantumornecrosisfactoridengansindrommetabolik |