BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS

Green nanocomposites containing bacterial cellulose and kaolin had been fabricated through a series of benign procedure utilising sodium hydroxide solution to purify the bacterial cellulose and distilled water as medium of mixing to obtain slurry of BC/K nanocomposites tha...

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Main Authors: , DWI WANNA, , Ir. M. Waziz Wildan, M.Sc., Ph.D.
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2014
Subjects:
ETD
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author , DWI WANNA
, Ir. M. Waziz Wildan, M.Sc., Ph.D.
author_facet , DWI WANNA
, Ir. M. Waziz Wildan, M.Sc., Ph.D.
author_sort , DWI WANNA
collection UGM
description Green nanocomposites containing bacterial cellulose and kaolin had been fabricated through a series of benign procedure utilising sodium hydroxide solution to purify the bacterial cellulose and distilled water as medium of mixing to obtain slurry of BC/K nanocomposites that were further moulded into becoming sheets. Increasing the amount of the bacterial cellulose improved the mechanical properties of the nanocomposites including modulus of elasticity, strength, strain, and toughness due to the solid ultrafine network fibres stabilised with hydrogen bonds. The nanocomposites possess a nanoporous structure supported by their hydrophilic property which is an ideal criteria for providing an optimal wound healing environment including, but not limited to, having an ability to maintain a moist environment for accelerating the healing process. The moisture levels concurrently plasticise the composites more effectively and thus the materials would be able to stretch and deform to a greater extremity before failing. Investigation on the performance of the nanocomposite for blood clotting potential was carried out using blood of mice. Increasing the amount of the kaolin shortened the blood clotting time. Higher kaolin content composites were found to have a higher percentage of smaller pores which allowed more of the blood to come into contact with kaolin particles and hence blood clotting occurred faster.
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spelling oai:generic.eprints.org:1208272016-03-04T07:55:06Z https://repository.ugm.ac.id/120827/ BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS , DWI WANNA , Ir. M. Waziz Wildan, M.Sc., Ph.D. ETD Green nanocomposites containing bacterial cellulose and kaolin had been fabricated through a series of benign procedure utilising sodium hydroxide solution to purify the bacterial cellulose and distilled water as medium of mixing to obtain slurry of BC/K nanocomposites that were further moulded into becoming sheets. Increasing the amount of the bacterial cellulose improved the mechanical properties of the nanocomposites including modulus of elasticity, strength, strain, and toughness due to the solid ultrafine network fibres stabilised with hydrogen bonds. The nanocomposites possess a nanoporous structure supported by their hydrophilic property which is an ideal criteria for providing an optimal wound healing environment including, but not limited to, having an ability to maintain a moist environment for accelerating the healing process. The moisture levels concurrently plasticise the composites more effectively and thus the materials would be able to stretch and deform to a greater extremity before failing. Investigation on the performance of the nanocomposite for blood clotting potential was carried out using blood of mice. Increasing the amount of the kaolin shortened the blood clotting time. Higher kaolin content composites were found to have a higher percentage of smaller pores which allowed more of the blood to come into contact with kaolin particles and hence blood clotting occurred faster. [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , DWI WANNA and , Ir. M. Waziz Wildan, M.Sc., Ph.D. (2014) BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=60865
spellingShingle ETD
, DWI WANNA
, Ir. M. Waziz Wildan, M.Sc., Ph.D.
BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS
title BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS
title_full BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS
title_fullStr BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS
title_full_unstemmed BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS
title_short BACTERIAL CELLULOSE-KAOLIN NANOCOMPOSITES FOR APPLICATION AS BIOMEDICAL WOUND HEALING MATERIALS
title_sort bacterial cellulose kaolin nanocomposites for application as biomedical wound healing materials
topic ETD
work_keys_str_mv AT dwiwanna bacterialcellulosekaolinnanocompositesforapplicationasbiomedicalwoundhealingmaterials
AT irmwazizwildanmscphd bacterialcellulosekaolinnanocompositesforapplicationasbiomedicalwoundhealingmaterials