PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK Actinobacillus Actinomycetemcomitans (kajian secara in vitro)
Periodontitis is a bacterial infection disease that leads to reversible and irreversible damage of periodontal tissue. The main etiology of periodontitis is plaque bacteria A. actinomycetemcomitans, which acts as dominant bacteria in aggressive periodontitis. Elimination of bacteria with natural sub...
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Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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author | , ROSI NASTITI DARMAYANI , drg. Hendrawati, M.Kes. |
author_facet | , ROSI NASTITI DARMAYANI , drg. Hendrawati, M.Kes. |
author_sort | , ROSI NASTITI DARMAYANI |
collection | UGM |
description | Periodontitis is a bacterial infection disease that leads to reversible and
irreversible damage of periodontal tissue. The main etiology of periodontitis is
plaque bacteria A. actinomycetemcomitans, which acts as dominant bacteria in
aggressive periodontitis. Elimination of bacteria with natural substance that has
ability as antibacterial agent such as papaya leaf (Carica papaya L.) can be used
to prevent periodontitis. The aim of this study was to determine the effect of
papaya leaf (Carica papaya L.) extract against the growth of plaque bacteria A.
actinomycetemcomitans in vitro.
This study was using 20 samples that divided into 4 TSA petri dishes which
had 5 wells in each dish with 5 mm diameter. Bacterial suspensions of A.
actinomycetemcomitans were swabbed on the dishes then 50 μL papaya leaf
extract concentration of 2,5%, 5%, 10%, negative control (tween 2,5%), and
positive control (clorhexidine) were drop into each wells. The diameters of
inhibition zone were measured 3 times (horizontal, vertical, and diagonal) using a
sliding caliper with 0,05 accuracy, then the mean was determined. Data obtained
then analyzed by One Way ANOVA and LSD 0,05 tests.
The result of One Way ANOVA with p=0,00 (p<0,05) showed significant
difference that indicated there was an effect of papaya leaf extract against plaque
bacteria inhibition zone A. actinomycetemcomitans. The result of LSD 0,05 test
showed significant difference (p<0,05) between control and treatment groups,
and the difference among the concentrations of papaya leaf extract (2,5%, 5%,
10%) (p>0,05) was not significant. The conclusion from this study was that the
papaya leaf extract could inhibit the growth of plaque bacteria A.
actinomycetemcomitans. |
first_indexed | 2024-03-13T22:56:44Z |
format | Thesis |
id | oai:generic.eprints.org:121683 |
institution | Universiti Gadjah Mada |
last_indexed | 2024-03-13T22:56:44Z |
publishDate | 2013 |
publisher | [Yogyakarta] : Universitas Gadjah Mada |
record_format | dspace |
spelling | oai:generic.eprints.org:1216832016-03-04T08:42:37Z https://repository.ugm.ac.id/121683/ PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK Actinobacillus Actinomycetemcomitans (kajian secara in vitro) , ROSI NASTITI DARMAYANI , drg. Hendrawati, M.Kes. ETD Periodontitis is a bacterial infection disease that leads to reversible and irreversible damage of periodontal tissue. The main etiology of periodontitis is plaque bacteria A. actinomycetemcomitans, which acts as dominant bacteria in aggressive periodontitis. Elimination of bacteria with natural substance that has ability as antibacterial agent such as papaya leaf (Carica papaya L.) can be used to prevent periodontitis. The aim of this study was to determine the effect of papaya leaf (Carica papaya L.) extract against the growth of plaque bacteria A. actinomycetemcomitans in vitro. This study was using 20 samples that divided into 4 TSA petri dishes which had 5 wells in each dish with 5 mm diameter. Bacterial suspensions of A. actinomycetemcomitans were swabbed on the dishes then 50 μL papaya leaf extract concentration of 2,5%, 5%, 10%, negative control (tween 2,5%), and positive control (clorhexidine) were drop into each wells. The diameters of inhibition zone were measured 3 times (horizontal, vertical, and diagonal) using a sliding caliper with 0,05 accuracy, then the mean was determined. Data obtained then analyzed by One Way ANOVA and LSD 0,05 tests. The result of One Way ANOVA with p=0,00 (p<0,05) showed significant difference that indicated there was an effect of papaya leaf extract against plaque bacteria inhibition zone A. actinomycetemcomitans. The result of LSD 0,05 test showed significant difference (p<0,05) between control and treatment groups, and the difference among the concentrations of papaya leaf extract (2,5%, 5%, 10%) (p>0,05) was not significant. The conclusion from this study was that the papaya leaf extract could inhibit the growth of plaque bacteria A. actinomycetemcomitans. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , ROSI NASTITI DARMAYANI and , drg. Hendrawati, M.Kes. (2013) PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK Actinobacillus Actinomycetemcomitans (kajian secara in vitro). UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=61780 |
spellingShingle | ETD , ROSI NASTITI DARMAYANI , drg. Hendrawati, M.Kes. PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK Actinobacillus Actinomycetemcomitans (kajian secara in vitro) |
title | PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK
Actinobacillus Actinomycetemcomitans (kajian secara in vitro) |
title_full | PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK
Actinobacillus Actinomycetemcomitans (kajian secara in vitro) |
title_fullStr | PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK
Actinobacillus Actinomycetemcomitans (kajian secara in vitro) |
title_full_unstemmed | PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK
Actinobacillus Actinomycetemcomitans (kajian secara in vitro) |
title_short | PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI PLAK
Actinobacillus Actinomycetemcomitans (kajian secara in vitro) |
title_sort | pengaruh ekstrak daun pepaya carica papaya l terhadap pertumbuhan bakteri plak actinobacillus actinomycetemcomitans kajian secara in vitro |
topic | ETD |
work_keys_str_mv | AT rosinastitidarmayani pengaruhekstrakdaunpepayacaricapapayalterhadappertumbuhanbakteriplakactinobacillusactinomycetemcomitanskajiansecarainvitro AT drghendrawatimkes pengaruhekstrakdaunpepayacaricapapayalterhadappertumbuhanbakteriplakactinobacillusactinomycetemcomitanskajiansecarainvitro |