| Summary: | Dog (Canis familiaris) is a pet that should be given attention and
outpouring of affection. Dogs may experience injury or wound. One of herbal that
is widely used as wound medicine is binahong (Anredera cordifolia (Ten)
Steenis). The purpose of this research was to determine the microscopic
description of fibroblast cells and leukocytes in the incision wound of dog skin
who where treated white the ointment ethanol extract of binahong leaves
concentration of 5% and 10% are microscopic.
Four local female dogs used in this study. Prior research adapted to any
dog for a few days and were given ivermectin worming. Making a incisionmade
after adaptation is completed as much as 3 slices (A, B, and C) on each dog on the
left side of the abdomen in the vertical direction. A incision of group A as the
control, untreatment, a incision of group B was given the ointment binahong leaf
extract 5% ethanol extraction and a incision of group C was given an ointment
binahong leaf extract 10% ethanol extraction. On day 14 most of the wound
healing tissue samples taken measuring 2x2 cm, then put into 10% formalin
solution for histological examination. The tissue sample is sent to the
Mikroanatomi Laboratory of the Faculty of Veterinary Medicine to made
preparations for histology with Haematoxylin-Eosin staining (HE). Display
leukocyte and fibroblast cells was calculated and analyzed using ANOVA test with
significance level p < 0.05.
Results of microscopic examination of fibroblast and leukocyte cell
numbers in group B and group C less than in group A. Statistical analysis using
ANOVA showed no significant difference between the control group and
lubrication binahong leaf extract (5% and 10%). These results can be concluded
that the description of the wound healing canine skin slices treated with the
ointment of binahong leaves ethanol extract had healed.
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