Perubahan Kadar Kolesterol Total Serum dan Berat Badan Setelah Pemberian Capsaicin Pada Tikus Sprague Dawley Hiperkolesterolemia
the most controllable risk factors for coronary heart disease. Many studies develop the effective treatments to lowering total cholesterol levels and body weight, including capsaicin. But, the effect of capsaicin to the correlation between total cholesterol level and body weight in hypercholesterole...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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| Summary: | the most controllable risk factors for coronary heart
disease. Many studies develop the effective treatments
to lowering total cholesterol levels and body weight,
including capsaicin. But, the effect of capsaicin to
the correlation between total cholesterol level and
body weight in hypercholesterolemia subject never been
understood before.
Objectives: The aim of the present study was to assess
the correlation between total cholesterol level�s to
body weight after capsaicin administration in
hypercholesterolemia mice.
Methods: Two-month-old male Sprague dawley rats were
randomly assigned to three groups (n=5) according to
their treatments. The groups II and III were rendered
hypercholesterolemia by maintaining them on a high-fat
diet (A.D.II diet, lard 10%, yolk and olive oil) for 14
weeks, while group I were not induced (negative
controls). The total cholesterol and body weight were
measured before and after the administration of
capsaicin.
Results: The capsaicin group had a statistically
significant (-88.07 mg/dL |
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