OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL
Sambiloto (Andrographis paniculata Ness) has been to have efficacy in lowering blood sugar levels in the presence of the active substance andrographolide but the taste is very bitter. This study was aimed to determine the effect of both avicel PH 101 and aerosil as on the preparation on of granules...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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| _version_ | 1826047022621261824 |
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| author | , yullia sukawaty , Prof. Dr. Achmad Fudholi, DEA, Apt |
| author_facet | , yullia sukawaty , Prof. Dr. Achmad Fudholi, DEA, Apt |
| author_sort | , yullia sukawaty |
| collection | UGM |
| description | Sambiloto (Andrographis paniculata Ness) has been to have efficacy in
lowering blood sugar levels in the presence of the active substance
andrographolide but the taste is very bitter. This study was aimed to determine the
effect of both avicel PH 101 and aerosil as on the preparation on of granules of
aquous extract of sambiloto.
For this purpose the factorial design method was used in concentration of
avicel 40% and 90% and aerosil 0% and 20% of the weight of the extract.
Responses observed were flow rate, angle of repose, tapping index, water
absorben, density and moisture content.
The results showed that a mixed composition of avicel PH 101 and aerosil
granules that fulfill the optimum physical requirements was 80.08% and 4.29%,
with the observed responses were flow rate, angle of repose, tapping index, water
absorben, density and moisture content respectively. Dissolution results in
optimum formulation obtained in Q45 by 14,92% + 1,21. |
| first_indexed | 2024-03-13T23:03:25Z |
| format | Thesis |
| id | oai:generic.eprints.org:123415 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T23:03:25Z |
| publishDate | 2013 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:1234152016-03-04T08:45:06Z https://repository.ugm.ac.id/123415/ OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL , yullia sukawaty , Prof. Dr. Achmad Fudholi, DEA, Apt ETD Sambiloto (Andrographis paniculata Ness) has been to have efficacy in lowering blood sugar levels in the presence of the active substance andrographolide but the taste is very bitter. This study was aimed to determine the effect of both avicel PH 101 and aerosil as on the preparation on of granules of aquous extract of sambiloto. For this purpose the factorial design method was used in concentration of avicel 40% and 90% and aerosil 0% and 20% of the weight of the extract. Responses observed were flow rate, angle of repose, tapping index, water absorben, density and moisture content. The results showed that a mixed composition of avicel PH 101 and aerosil granules that fulfill the optimum physical requirements was 80.08% and 4.29%, with the observed responses were flow rate, angle of repose, tapping index, water absorben, density and moisture content respectively. Dissolution results in optimum formulation obtained in Q45 by 14,92% + 1,21. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , yullia sukawaty and , Prof. Dr. Achmad Fudholi, DEA, Apt (2013) OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=63526 |
| spellingShingle | ETD , yullia sukawaty , Prof. Dr. Achmad Fudholi, DEA, Apt OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL |
| title | OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL |
| title_full | OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL |
| title_fullStr | OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL |
| title_full_unstemmed | OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL |
| title_short | OPTIMASI FORMULA GRANUL EKSTRAK AIR HERBA SAMBILOTO (Andrographis paniculata Ness) MENGGUNAKAN AVICEL PH 101 DAN AEROSIL DENGAN METODE DESAIN FAKTORIAL |
| title_sort | optimasi formula granul ekstrak air herba sambiloto andrographis paniculata ness menggunakan avicel ph 101 dan aerosil dengan metode desain faktorial |
| topic | ETD |
| work_keys_str_mv | AT yulliasukawaty optimasiformulagranulekstrakairherbasambilotoandrographispaniculatanessmenggunakanavicelph101danaerosildenganmetodedesainfaktorial AT profdrachmadfudholideaapt optimasiformulagranulekstrakairherbasambilotoandrographispaniculatanessmenggunakanavicelph101danaerosildenganmetodedesainfaktorial |